Items where Author is Laws, Andrew

Article

Almond, Michael, Suleiman, Mustapha G., Hawkins, Matthew, Winder, Daniel, Robshaw, Thomas, Waddoups, Megan, Humphreys, Paul and Laws, Andrew P. (2018) Developing cellulosic waste products as platform chemicals: protecting group chemistry of α-glucoisosaccharinic acid. Carbohydrate Research, 455. pp. 97-105. ISSN 0008-6215

Charles, Christopher J., Rout, Simon P., Laws, Andrew P., Jackson, Brian R., Boxall, Sally A. and Humphreys, Paul N (2017) The impact of biofilms upon surfaces relevant to an intermediate level radioactive waste geological disposal facility under simulated near field conditions. Geosciences, 7 (3). p. 57. ISSN 2076-3263

Charles, C.J., Rout, Simon P., Patel, K.A., Akbar, S., Laws, Andrew P., Jackson, B.R., Boxall, S.A. and Humphreys, Paul (2017) Floc formation reduces the pH stress experienced by microorganisms living in alkaline environments. Applied and Environmental Microbiology, 83 (6). ISSN 0099-2240

Balzaretti, Silvia, Taverniti, Valentina, Guglielmetti, Simone, Fiore, Walter, Minuzzo, Mario, Ngo, Hansel N., Ngere, Judith B., Sadiq, Sohaib, Humphreys, Paul N and Laws, Andrew P. (2017) A novel rhamnose-rich hetero-exopolysaccharide isolated from Lactobacillus paracasei DG activates THP-1 human monocytic cells. Applied and Environmental Microbiology, 83 (2). AEM.02702-16. ISSN 0099-2240

Scotson, James L., Andrews, Benjamin I., Laws, Andrew P. and Page, Michael I. (2016) Phosphorothioate anti-sense oligonucleotides: the kinetics and mechanism of the sulfurisation of phosphites by phenylacetyl disulfide (PADS). Organic and Biomolecular Chemistry, 14 (46). pp. 10840-10847. ISSN 1477-0539

Scotson, James, Laws, Andrew P., Andrews, Benjamin I. and Page, Michael I. (2016) Phosphorothioate Anti-sense Oligonucleotides: The Kinetics and Mechanism of the Generation of the Sulfurising Agent from Phenylacetyl Disulfide (PADS). Organic & Biomolecular Chemistry (35). pp. 8301-8308. ISSN 1477-0520

Almond, Michael, Belton, Daniel J., Humphreys, Paul and Laws, Andrew P. (2016) A study of the metal binding capacity of saccharinic acids formed during the alkali catalysed decomposition of cellulosic materials: nickel complexation by glucoisosaccharinic acids and xyloisosaccharinic acids. Carbohydrate Research, 427. pp. 48-54. ISSN 0008-6215

AL-Jasim, Ammar, Davis, Mark, Cossar, Douglas, Miller, Timothy, Humphreys, Paul and Laws, Andrew P. (2016) Isolation of sophorose during sophorolipid production and studies of its stability in aqueous alkali: epimerisation of sophorose to 2-O-β-d-glucopyranosyl-d-mannose. Carbohydrate Research, 421. pp. 46-54. ISSN 0008-6215

Jowiya, Waheed, Brunner, Katja, Abouelhadid, Sherif, Hussain, Haitham A., Nair, Sean P., Sadiq, Sohaib, Williams, Lisa K., Trantham, Emma K., Stephenson, Holly, Wren, Brendan W., Bajaj-Elliott, Mona, Cogan, Tristan A., Laws, Andrew P., Wade, Jim, Dorrell, Nick and Allan, Elaine (2015) Pancreatic Amylase is an Environmental Signal for Regulation of Biofilm Formation and Host Interaction inCampylobacter jejuni. Infection and Immunity, 83 (12). IAI.01064-15. ISSN 0019-9567

Pan, Chongle, Rout, Simon P., Charles, Christopher J., Doulgeris, Charalampos, McCarthy, Alan J., Rooks, Dave J., Loughnane, J. Paul, Laws, Andrew P. and Humphreys, Paul N (2015) Anoxic Biodegradation of Isosaccharinic Acids at Alkaline pH by Natural Microbial Communities. PLoS ONE, 10 (9). e0137682. ISSN 1932-6203

Rout, Simon, Charles, Christopher, Garratt, Eva, Laws, Andrew P., Gunn, John and Humphreys, Paul (2015) Evidence of the Generation of Isosaccharinic Acids and Their Subsequent Degradation by Local Microbial Consortia within Hyper-Alkaline Contaminated Soils, with Relevance to Intermediate Level Radioactive Waste Disposal. PLoS ONE, 10 (3). e0119164. ISSN 1932-6203

Patten, D.A. and Laws, Andrew P. (2015) Lactobacillus-produced exopolysaccharides and their potential health benefits: a review. Beneficial Microbes, 6 (4). pp. 457-471. ISSN 1876-2883

Alba, K., Laws, Andrew P. and Kontogiorgos, Vassilis (2015) Isolation and characterization of acetylated LM-pectins extracted from okra pods. Food Hydrocolloids, 43. pp. 726-735. ISSN 0268005X

Janssen, Paul Jaak, Rout, Simon P., Radford, Jessica, Laws, Andrew P., Sweeney, Francis, Elmekawy, Ahmed, Gillie, Lisa J. and Humphreys, Paul N. (2014) Biodegradation of the Alkaline Cellulose Degradation Products Generated during Radioactive Waste Disposal. PLoS ONE, 9 (9). e107433. ISSN 1932-6203

Rout, Simon, Radford, Jessica, Laws, Andrew P., Sweeney, Francis, Elmekawy, Ahmed A., Gillie, Lisa .J. and Humphreys, Paul (2014) Biodegradation of the Alkaline Cellulose Degradation Products Generated during Radioactive Waste Disposal. PLoS ONE, 9 (9). e107433. ISSN 1932-6203

Alhudhud, M, Humphreys, Paul and Laws, Andrew P. (2014) Development of A Growth Medium Suitable for Exopolysaccharide Production and Structural Characterisation by Bifidobacteria animalis ssp. lactis. Journal of Microbiological Methods, 100. pp. 93-98. ISSN 0167-7012

Patten, D A, Leivers, Shaun, Chadha, Marcus J., Maqsood, Mohammed, Humphreys, Paul, Laws, A P and Collett, Andrew (2014) The structure and immunomodulatory activity on intestinal epithelial cells of the EPSs isolated from Lactobacillus helveticus sp. Rosyjski and Lactobacillus acidophilus sp. 5e2. Carbohydrate Research, 384. pp. 119-127. ISSN 00086215

Almond, Michael, Shaw, Paul B., Humphreys, Paul, Chadha, Marcus J., Niemelä, Klaus and Laws, Andrew P. (2012) Behavior of xyloisosaccharinic acid and xyloisosaccharino-1,4-lactone in aqueous solutions at varying pHs. Carbohydrate Research, 363. pp. 51-57. ISSN 00086215

Ponomarov, Oleksandr, Laws, Andrew P and Hanusek, Jiri (2012) 1,2,4-Dithiazole-5-ones and 5-thiones as Efficient Sulfurizing Agents of Phosphorus (III) Compounds – A Kinetic Comparative Study. Organic and Biomolecular Chemistry. ISSN 1477-0539

Leivers, Shaun, Hidalgo-Cantabrana, Claudio, Robinson, Glenn, Margolles, Abelardo, Ruas-Madiedo, Patricia and Laws, Andrew P. (2011) Structure of the high molecular weight exopolysaccharide produced by Bifidobacterium animalis subsp. lactis IPLA-R1 and sequence analysis of its putative eps cluster. Carbohydrate Research, 346 (17). pp. 2710-2717. ISSN 00086215

Laws, Andrew P., Leivers, Shaun, Chacon-Romero, Mariana and Chadha, Marcus J. (2009) Variation in the molecular mass of exopolysaccharides during the time course of extended fermentations of skimmed milk by lactic acid bacteria. International Dairy Journal, 19 (12). pp. 768-771. ISSN 0958-6946

Russell, Mark A., Laws, Andrew P., Atherton, John H. and Page, Michael I. (2009) The kinetics and mechanism of the acid-catalysed detritylation of nucleotides in non-aqueous solution. Organic and Biomolecular Chemistry, 7 (1). pp. 52-57. ISSN 1477-0539

Russell, Mark A., Laws, Andrew P., Atherton, John H. and Page, Michael I. (2008) The mechanism of the phosphoramidite synthesis of polynucleotides. Organic and Biomolecular Chemistry, 6 (18). pp. 3270-3275. ISSN 1477-0539

Laws, Andrew P., Chadha, Marcus J., Chacon-Romero, Mariana, Marshall, Valerie M. and Maqsood, Mohammed (2008) Determination of the structure and molecular weights of the exopolysaccharide produced by Lactobacillus acidophilus 5e2 when grown on different carbon feeds. Carbohydrate Research, 343 (2). pp. 301-307. ISSN 00086215

Clayton, Hayley J., Harding, Lindsay P., Irvine, J.P., Jeffery, John C., Riis-Johannessen, Thomas, Laws, Andrew P., Rice, Craig R. and Whitehead, Martina (2008) Metal-specific allosteric activation and deactivation of a diamine. Chemical Communications (1). p. 108. ISSN 1364-548X

Hanusek, Jifi, Russell, Mark A., Laws, Andrew P. and Page, Michael I. (2007) Evidence for the formation of isothiocyanate during sulphurisation of triphenyl phosphines using xanthane hydride. Tetrahedron Letters, 48 (3). pp. 417-419. ISSN 0040-4039

Hanusek, Jifi, Russell, Mark A., Laws, Andrew P., Jansa, Petr, Atherton, John H., Fettes, Kevin and Page, Michael I. (2007) Mechanism of the sulphurisation of phosphines and phosphites using 3-amino-1,2,4-dithiazole-5-thione (Xanthane Hydride). Organic and Biomolecular Chemistry, 5 (3). pp. 478-484. ISSN 1477-0539

Badarau, Adriana, Llinas, Antonio, Laws, Andrew P., Damblon, Christian and Page, Michael I. (2005) Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics. Biochemistry, 44 (24). pp. 8578-8589. ISSN 1520-4995

Llinas, Antonio, Ahmed, Naveed, Cordaro, Massimiliano, Laws, Andrew P., Frere, Jean-Marie, Delmarcelle, Michael, Silvaggi, Nicholas R., Kelly, Judith A. and Page, Michael I. (2005) The inactivation of bacterial DD-peptidase by β-sultams. Biochemistry, 44 (21). pp. 7738-7746. ISSN 1520-4995

Tsang, Wing Y., Ahmed, Naveed, Harding, Lindsay P., Hemming, Karl, Laws, Andrew P. and Page, Michael I. (2005) Acylation versus sulfonylation in the inhibition of elastase by 3-oxo-beta-sultams. Journal of the American Chemical Society, 127 (25). pp. 8946-8947. ISSN 1520-5126

Tsang, W.Y., Ahmed, Naveed, Hinchliffe, Paul S., Wood, J. Matthew, Harding, Lindsay P., Laws, Andrew P. and Page, Michael I. (2005) Different transition-state structures for the reactions of β-lactams and analogous β-sultams with serine β-lactamases. Journal of the American Chemical Society, 127 (49). pp. 17556-17564. ISSN 1520-5126

Harding, Lindsay P., Marshall, Valerie M., Hernandez, Y., Gu, Y., Maqsood, Mohammed, McLay, N. and Laws, Andrew P. (2005) Structural characterisation of the highly branched exopolysaccharide produced by Lactobacillus delbrueckii subsp. Bulgaricus NCFB2074. Carbohydrate Research, 340 (6). pp. 1107-1111. ISSN 0008-6215

Vaningelgem, Frederik, Van der Meulen, Roel, Zamfir, Medana, Adriany, Tom, Laws, Andrew P. and De Vuyst, Luc (2004) Streptococcus thermophilus ST 111 produces a stable high-molecular-mass exopolysaccharide in milk-based medium. International Dairy Journal, 14 (10). pp. 857-864. ISSN 09586946

Page, Michael I., Hinchliffe, Paul S., Wood, J. Matthew, Harding, Lindsay P. and Laws, Andrew P. (2003) Novel mechanism of inhibiting b-lactamases by sulfonylation using b-sultams. Bioorganic & Medicinal Chemistry Letters, 13 (24). pp. 4489-4492. ISSN 0960-894X

Harding, Lindsay P., Marshall, Valerie M., Elvin, M., Gu, Y. and Laws, Andrew P. (2003) Structural characterisation of a perdeuteriomethylated exoploysaccharide by NMR spectroscopy: characterisation of the novel exopolysaccharide produced by Lactobacillus delbrueckii subsp. Bulgaricus EU23. Carbohydrate Research, 338 (1). pp. 61-67. ISSN 0008-6215

Wood, J. Matthew, Hinchliffe, Paul S., Laws, Andrew P. and Page, Michael I. (2002) Reactivity and the mechanism of reactions of β-sultams with Nucleophiles. Journal of the Chemical Society Perkins Transactions 2. pp. 938-946. ISSN 1364-5471

Laws, Andrew P. and Marshall, Valerie M. (2001) The relevance of exopolysaccharides to the rheological properties in milk fermented with ropy strains of lactic acid bacteria. International Dairy Journal, 11 (9). pp. 709-721. ISSN 0958-6946

Degeest, B., Vaningelgem, Frederik, Laws, Andrew P. and De Vuyst, Luc (2001) UDP-N-Acetylglucosamine 4-Epimerase Activity Indicates the Presence of N-Acetylgalactosamine in Exopolysaccharides of Streptococcus thermophilus Strains. Applied and Environmental Microbiology, 67 (9). pp. 3976-3984. ISSN 0099-2240

Laws, Andrew P., Gu, Y. and Marshall, Valerie M. (2001) Biosynthesis, characterisation, and design of bacterial exopolysaccharides from lactic acid bacteria. Biotechnology Advances, 19 (8). pp. 597-625. ISSN 0734-9750

Bounaga, Sakina, Galleni, Moreno, Laws, Andrew P. and Page, Michael I. (2001) Cysteinyl peptide Inhibitors of Bacillus cereus Zinc β-Lactamase. Bioorganic & Medicinal Chemistry Letters, 9 (2). pp. 503-507. ISSN 0960-894X

Marshall, Valerie M., Laws, Andrew P., Gu, Y., Levander, F., Radstrom, P., De Vuyst, Luc, Degeest, B., Vaningelgem, Frederik, Dunn, H. and Elvin, M. (2001) Exopolysaccharide-producing strains of thermophilic lactic acid bacteria cluster into groups according to their EPS structure. Letters in Applied Microbiology, 32 (6). pp. 433-435. ISSN 02668254

Marshal, V.M., Dunn, H., Elvin, M., McLay, N., Gu, Y. and Laws, Andrew P. (2001) Structural characterisation of the exopolysaccharide produced by Streptococcus Thermophilis EU20. Carbohydrate Research, 331 (4). pp. 413-422. ISSN 0008-6215

Slater, Martin J., Laws, Andrew P. and Page, Michael I. (2001) The relative catalytic efficiency of β-lactamase catalysed acyl and phosphyl transfer. Bioorganic Chemistry, 29. pp. 77-95. ISSN 0045-2068

Laws, Andrew P. and Marshall, Valerie M. (2001) The relevance of exopolysaccharides to the rheological properties in milk fermented with ropy strains of lactic acid bacteria. International Dairy Journal, 11. pp. 709-721. ISSN 0958-6946

Page, Michael I. and Laws, Andrew P. (2000) The Chemical Reactivity of β-Lactams, β-Sultams and β-Phospholactams. Tetrahedron, 56 (31). pp. 5631-5637. ISSN 0040-4020

Baxter, Nicholas J., Rigoreau, Laurent J.M., Laws, Andrew P. and Page, Michael I. (2000) Reactivity and Mechanism in the Hydrolysis of β-Sultams. Journal of the American Chemical Society, 122 (14). pp. 3375-3380. ISSN 1520-5126

Page, Michael I. and Laws, Andrew P. (1998) The mechanism of catalysis and the inhibition of β-lactamases. Chemical Communications (16). pp. 1609-1617. ISSN 1359-7345

Bounaga, Sakina, Laws, Andrew P., Galleni, Moreno and Page, Michael I. (1998) The mechanism of catalysis and the inhibition of the Bacillus cereus zinc-dependent b-lactamase. Biochemical Journal, 331 (3). pp. 703-711. ISSN 0264-6021

Baxter, Nicholas J., Laws, Andrew P., Rigoreau, Laurent and Page, Michael I. (1996) The hydrolytic reactivity of B-sultams. Journal of the Chemical Society, Perkin Transactions 2 (11). p. 2245. ISSN 1472-779X

Laws, Andrew P. and Page, Michael I. (1996) The chemistry and structure-activity relationships of C3-quaternary ammonium cephem antibiotics. Journal of Chemotherapy, 8. pp. 7-22. ISSN 1120-009X

Layland, Nicola J., Laws, Andrew P., Vilanova, Bartolomé and Page, Michael I. (1995) Penicillin 3-aldehyde is a good substrate and not an inhibitor of ?-lactamases A and C. Journal of the Chemical Society, Perkin Transactions 2 (5). pp. 869-870. ISSN 1472-779X

Page, Michael I., Laws, Andrew P., Slater, Martin J. and Stone, J.R. (1995) Reactivity of β-lactams and phosphonamidates and reactions with β-lactamase. Pure and Applied Chemistry, 67 (5). pp. 711-717. ISSN 0033-4545

Barton, Patrick, Laws, Andrew P. and Page, Michael I. (1994) Structure-activity relationships in the esterase-catalysed hydrolysis and transesterification of esters and lactones. Journal of the Chemical Society, Perkin Transactions 2 (9). pp. 2021-2029. ISSN 1472-779X

Laws, Andrew P., Stone, J.R. and Page, Michael I. (1994) Large rate enhancement for the hydrolysis of a four-membered ring phosphonamidate. Chemical Communications (10). pp. 1223-1224. ISSN 1359-7345

Laws, Andrew P., Page, Michael I. and Slater, Martin J. (1993) The mechanism of reactions catalysed by the serine β-lactamases. Bioorganic & Medicinal Chemistry Letters, 3 (11). pp. 2317-2322. ISSN 0960-894X

Laws, Andrew P., Layland, Nicola J., Proctor, David G. and Page, Michael I. (1993) The roles of the carboxy group in ?-lactam antibiotics and lysine 234 in ?-lactamase I. Journal of the Chemical Society, Perkin Transactions 2 (1). pp. 17-21. ISSN 1472-779X

Laws, Andrew P. and Page, Michael I. (1989) The effect of the carboxy group on the chemical and ?-lactamase reactivity of ?-lactam antibiotics. Journal of the Chemical Society, Perkin Transactions 2 (10). pp. 1577-1581. ISSN 1472-779X

Book Chapter

Page, Michael I. and Laws, Andrew P. (1990) Molecular recognition in beta lactamases. In: Molecular mechanisms in bioorganic processes. Royal Society of Chemistry, pp. 319-330. ISBN 9780851869469

Monograph

Humphreys, P N, Laws, A P and Dawson, J (2010) A Review of Cellulose Degradation and the Fate of Degradation Products Under Repository Conditions. Technical Report. Nuclear Decommissioning Authority (NDA), Cumbria, UK.