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Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences

Parkinson, John A., Scott, Fraser J., Suckling, Colin J. and Wilson, Gail (2013) Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences. MedChemComm, 4 (7). p. 1105. ISSN 2040-2503
Abstract

An antibacterial DNA minor groove binder is shown by NOE experiments to self-associate in aqueous solution at temperatures up to 80 °C in an anti-parallel, head-to-tail orientation as found in binding to duplex DNA oligomers

Information
URI:
https://eprints.hud.ac.uk/id/eprint/32654
Title:
Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences
Creators:
Parkinson, John A., Scott, Fraser J., Suckling, Colin J. and Wilson, Gail
Identification Number:
10.1039/c3md00071k
Official URL:
https://doi.org/10.1039/c3md00071k
Date:
20 May 2013
Subjects:
Q Science > QD Chemistry
Schools:
School of Applied Sciences
Library
Item Type:
Article
Depositing User:
Fraser Scott
Date Deposited:
15 Aug 2017 12:46
Revision:
11
Last Modified:
28 Aug 2021 12:19
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