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A thiazine-S-oxide, Staudinger/aza-Wittig based synthesis of benzodiazepines and benzothiadiazepines

Anwar, Balques, Grimsey, Paul, Hemming, Karl, Krajniewski, Matthew and Loukou, Christina (2000) A thiazine-S-oxide, Staudinger/aza-Wittig based synthesis of benzodiazepines and benzothiadiazepines. Tetrahedron Letters, 41 (51). pp. 10107-10110. ISSN 0040-4039
Abstract

A new approach to the synthesis of imine containing 1,2,5-benzothiadiazepine-1,1-dioxides and 1,4-benzodiazepin-5-ones using iminophosphoranyl thiazine-S-oxides as precursors is reported. Key steps include a Staudinger reaction, an aza-Wittig reaction and the conversion of a thiazine-S-oxide into an amino ketone via a [2,3] sigmatropic rearrangement

Information
URI:
https://eprints.hud.ac.uk/id/eprint/2247
URI:
https://eprints.hud.ac.uk/id/eprint/2247
URI:
https://eprints.hud.ac.uk/id/eprint/2247
URI:
https://eprints.hud.ac.uk/id/eprint/2247
URI:
https://eprints.hud.ac.uk/id/eprint/2247
Title:
A thiazine-S-oxide, Staudinger/aza-Wittig based synthesis of benzodiazepines and benzothiadiazepines
Creators:
Anwar, Balques, Grimsey, Paul, Hemming, Karl, Krajniewski, Matthew and Loukou, Christina
Identification Number:
https://doi.org/10.1016/S0040-4039(00)01797-4
Official URL:
http://dx.doi.org/10.1016/S0040-4039(00)01797-4
Date:
2000
Subjects:
Q Science > Q Science (General)
Q Science > QD Chemistry
Schools:
School of Applied Sciences
School of Applied Sciences > Biomolecular Sciences Research Centre
Library
Item Type:
Article
Depositing User:
Sara Taylor
Date Deposited:
16 Oct 2008 11:15
Revision:
14
Last Modified:
28 Aug 2021 10:42
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