Chemoenzymatic dynamic kinetic resolution of secondary amines

Stirling, Matthew J., Blacker, J. and Page, Michael I. (2007) Chemoenzymatic dynamic kinetic resolution of secondary amines. Tetrahedron Letters, 48 (7). pp. 1247-1250. ISSN 0040-4039

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Abstract

The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

Information

URI:

https://eprints.hud.ac.uk/id/eprint/177

Title:

Chemoenzymatic dynamic kinetic resolution of secondary amines

Creators:

Stirling, Matthew J., Blacker, J. and Page, Michael I.

Identification Number:

https://doi.org/10.1016/j.tetlet.2006.12.032

Official URL:

http://dx.doi.org/10.1016/j.tetlet.2006.12.032

Date: