Abstract
RVD in ZR-75-1 cells, epithelial-derived human breast cancer cells, is HCO3- dependent and involves the parallel activation of the K+ and volume-regulated anion channel (VRAC; Nicholl et al. 2001). Preliminary data indicated that the mechanisms of RVD were calcium (Ca2+) dependent, although the exact nature is unknown. This study investigated the Ca2+ dependency of RVD in ZR-75-1 cells using the video imaging technique
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