Synthesis of cleviolide and the scobinolides

Hollingworth, Gregory and Sweeney, Joseph B. (1993) Synthesis of cleviolide and the scobinolides. Synlett (7). pp. 463-465. ISSN 0936-5214

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Abstract

The polyunsaturated 2(5H)-furanone natural products cleviolide (1) and (E)- and (Z)-scobinolide (2) and (3) have been efficiently synthesized in convergent fashion via palladiumcatalyzed coupling of 4-tributylstannyl-2(5H)-furanone (4) and 1-iodo-4-methylpent-3-en-1-yne (5).

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URI:

https://eprints.hud.ac.uk/id/eprint/15416

URI:

https://eprints.hud.ac.uk/id/eprint/15416

URI:

https://eprints.hud.ac.uk/id/eprint/15416

Title:

Synthesis of cleviolide and the scobinolides

Creators:

Hollingworth, Gregory and Sweeney, Joseph B.

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