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Ring-opening of n-tosyl aziridines by sulfur-stabilized nucleophiles

Osborn, Helen, Howson, William and Sweeney, Joseph B. (1993) Ring-opening of n-tosyl aziridines by sulfur-stabilized nucleophiles. Synlett, 9. pp. 675-676. ISSN 0936-5214
Abstract

The novel ring-opening reaction of enantiopure N-activated aziridines 1 with anions 2 derived from 1,3-dithiane proceeds regiospecifically at the carbon of lesser substitution. The ring-opened products 3 may efficiently be converted to homochiral 2-tosylaminocarbonyl compounds 4.

Information
URI:
https://eprints.hud.ac.uk/id/eprint/15414
URI:
https://eprints.hud.ac.uk/id/eprint/15414
Title:
Ring-opening of n-tosyl aziridines by sulfur-stabilized nucleophiles
Creators:
Osborn, Helen, Howson, William and Sweeney, Joseph B.
Identification Number:
10.1055/s-1993-22568
Official URL:
http://dx.doi.org/10.1055/s-1993-22568
Date:
September 1993
Subjects:
Q Science > QD Chemistry
Schools:
School of Applied Sciences
Library
Item Type:
Article
Depositing User:
Joseph Sweeney
Date Deposited:
17 Oct 2012 11:45
Revision:
8
Last Modified:
28 Aug 2021 11:22
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