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Number of items: 35.


Anwar, Balques, Grimsey, Paul, Hemming, Karl, Krajniewski, Matthew and Loukou, Christina (2000) A thiazine-S-oxide, Staudinger/aza-Wittig based synthesis of benzodiazepines and benzothiadiazepines. Tetrahedron Letters, 41 (51). pp. 10107-10110. ISSN 0040-4039


Hemming, Karl (2017) The Synthesis and Chemistry of Azolobenzodiazepines. In: Advances in Heterocyclic Chemistry. Advances in Heterocyclic Chemistry, 123 (123). Academic Press, pp. 63-103. ISBN 9780128120927

Hamasharif, Muslih S., Smith, Oliver, Curran, Collette and Hemming, Karl (2017) N-Alkylation and Aminohydroxylation of 2-Azidobenzenesulfonamide gives a Pyrrolobenzothiadiazepine precursor whereas attempted N-Alkylation of 2-Azidobenzamide gives Benzotriazinones and Quinazolinones. ACS Omega, 2 (3). pp. 1222-1231. ISSN 2470-1343

Hemming, Karl, Blackburn, Jack, Molyneux, Gary, Pitard, Arnaud, Rice, Craig R., Page, Michael I., Afshinjavid, S., Javid, Farideh A., Coles, Simon J. and Horton, Peter N. (2016) Synthesis, Conformation and Antiproliferative Activity of Isothiazoloisoxazole 1,1-dioxides. Organic and Biomolecular Chemistry, 14. pp. 2134-2144. ISSN 1477-0539

Hemming, Karl, Jamshaid, Faisal and Khan, Musharraf (2015) 2-Methylsulfanylbenzo[f]isoquinoline. Molbank, 2015 (M860). pp. 1-5. ISSN 1422-8559

Hemming, Karl, Chambers, Christopher Steven, Hamasharif, Muslih S., Joãoa, Heidi, Khan, Musharraf N., Patel, Nilesh, Airley, Rachel and Day, Sharn (2014) Azide based routes to tetrazolo and oxadiazolo derivatives of pyrrolobenzodiazepines and pyrrolobenzothiadiazepines. Tetrahedron, 70 (40). pp. 7306-7317. ISSN 0040-4020

Hemming, Karl, Jamshaid, Faisal and Chambers, Christopher Steven (2014) Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines. Molecules, 19 (10). pp. 16737-16756. ISSN 1420-3049

Hemming, Karl, Kondakal, Vishnu and Qamar, M. Ilyas (2012) The synthesis of hydroxy-pyrrolizidines and indolizidines from cyclopropenones: towards hyacinthacines, australines and jenamidines. Tetrahedron Letters, 53 (32). pp. 4100-4103. ISSN 0040-4039

Hemming, Karl, Khan, Musharraf, Kondakal, Vishnu, Rice, Craig R., Pitard, Arnaud and Qamar, Muhammad Ilyas (2012) Pyridines from azabicyclo[3.2.0]hept-2-en-4-ones through a proposed azacyclopentadienone. Organic Letters, 14 (1). pp. 126-129. ISSN 15237060

Hemming, Karl (2011) Heterocyclic chemistry. Annual Reports Section B Organic Chemistry, 107 (1). pp. 118-137. ISSN 0069-3039

Hemming, Karl (2010) Heterocyclic Chemistry. Annual Reports on the Progress of Chemistry Section B, 106. pp. 136-155. ISSN 0069-3030

Hemming, Karl (2010) Intramolecular 1,3-dipolar cycloaddition as a route to triazolobenzodiazepines and pyrrolobenzodiazepines. Tetrahedron Letters, 51 (37). pp. 4859-4861. ISSN 0040-4039

Hemming, Karl (2009) Heterocyclic chemistry. Annual Reports Section "B" (Organic Chemistry), 105. pp. 129-149. ISSN 00693030

Hemming, Karl (2008) 1,2,4-Oxadiazoles. In: Comprehensive Heterocyclic Chemistry III. Elsevier, London, UK, pp. 243-314. ISBN 0-08-044991-3

Hemming, Karl (2008) Bicyclic 6-6 systems: five or more heteroatoms. In: Comprehensive Heterocyclic Chemistry III. Elsevier, London, UK, pp. 1093-1134. ISBN 0-08-044991-3

Hemming, Karl, O'Gorman, P.A. and Page, Michael I. (2006) The synthesis of azabicyclo[4.2.1]nonenes by the addition of a cyclopropenone to 4-vinyl substituted 1-azetines-isomers of the homotropane nucleus. Tetrahedron Letters, 47. pp. 425-428. ISSN 0040-4039

Hemming, Karl and Loukou, Christina (2005) Synthetic approaches to 1,2,5-benzothiadiazepine 1,1-dioxides - sulfonamide analogues of the 1,4-benzodiazepines. Journal of chemical research (1). pp. 1-12. ISSN 1747-5198

Hemming, Karl and Loukou, Christina (2004) The synthesis of bicyclic 1,2,3,4-tetrahydro-1,4-benzodiazepin-5-ones from 2-(o-nitrobenzyl)-1,2-thiazine-1-oxide precursors. Tetrahedron, 60. pp. 3349-3357. ISSN 0040-4020

Hemming, Karl, Loukou, Christina, Elkatip, Sinem and Smalley, Robert K. (2004) The First aza-Wittig Reaction Involving a non-Cumulated Sulfoxy Group. Synlett (1). pp. 101-105. ISSN 09365214

Hemming, Karl and Patel, N. (2004) The synthesis of pyrrolo[1,2,b][1,2,5]benzothiadiazepines from 1,2-thiazine 1-oxides-sulfonamide analogues of the pyrrolobenzodiazepine antitumour natural products. Tetrahedron Letters, 45. pp. 7553-7556. ISSN 0040-4039

Hemming, Karl (2003) 1,2,4-oxadiazoles. In: Science of Synthesis: Houben-Weyl Methods of Molecular Transformations. Thieme, Stuttgart, Germany, pp. 1-56. ISBN 9780865779440

Hemming, Karl (2001) Recent developments in the synthesis, chemistry and applications of the fully unsaturated 1,2,4-oxadiazoles. Journal of chemical research, 2001 (6). pp. 209-218. ISSN 1747-5198

Hemming, Karl, Bevan, Matthew J., Loukou, Christina, Patel, Snahal D. and Renaudeau, Denis (2000) A One-Pot Aza-Wittig Based Solution and Polymer Supported Route to Amines. Synlett, 2000 (11). pp. 1565-1568. ISSN 09365214

Hemming, Karl, Morgan, Dexter T. and Smalley, Robert K. (2000) A clean and efficient synthesis of 5-(2′-fluoro-2′,3′-dimethylbutan-3′-yl) substituted 1,2,4-oxadiazoles using silver tetrafluoroborate as a fluorodesulfurization reagent. Journal of Fluorine Chemistry, 106 (1). pp. 83-86. ISSN 00221139


Khan, Musharraf, Pitard, Arnaud, O'Gorman, P.A. and Hemming, Karl (2013) 1,2,4-Oxadiazoles from cycloreversions of oxadiazabicyclo[3.2.0]heptenes: 1-azetines as thiocyanate equivalents. Tetrahedron, 69 (4). pp. 1279-1284. ISSN 0040-4020


Loukou, Christina, Hemming, Karl, Patel, N. and Foucher, V. (2005) The synthesis of 1,2,5-benzothiadiazepine 1,1-dioxides from 1,2-thiazine 1-oxides. Journal of Sulfur Chemistry, 26 (6). pp. 455-479. ISSN 1741-5993


O’Gorman, Paul A., Chen, Ting, Cross, Hannah E., Naeem, Salima, Pitard, Arnaud, Qamar, M. Ilyas and Hemming, Karl (2008) A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines. Tetrahedron Letters, 49 (44). pp. 6316-6319. ISSN 0040-4039


Patel, Nilesh, Chambers, Christopher Steven and Hemming, Karl (2009) The synthesis of benzothiadiazines, benzothiadiazepines and benzothiadiazocines from intramolecular azide reactions and iodocyclisations. Synlett, 2009 (18). pp. 3043-3047. ISSN 09365214


Tsang, Wing Y., Ahmed, Naveed, Hemming, Karl and Page, Michael I. (2008) An activated sulfonylating agent that undergoes general base-catalyzed hydrolysis by amines in preference to aminolysis. The Journal of Organic Chemistry, 73 (12). pp. 4504-4512. ISSN 00223263

Tsang, Wing Y., Ahmed, Naveed, Hemming, Karl and Page, Michael I. (2007) Reactivity and selectivity in the inhibition of elastase by 3-oxo-β-sultams and in their hydrolysis. Organic and Biomolecular Chemistry, 5 (24). pp. 3993-4000. ISSN 1477-0539

Tsang, Wing Y., Ahmed, Naveed, Hemming, Karl and Page, Michael I. (2005) Competitive endo- and exo-cyclic C-N fission in the hydrolysis of N-aroyl β-lactams. Canadian Journal of Chemistry, 83 (9). pp. 1432-1439. ISSN 1480-3291

Tsang, Wing Y., Ahmed, Naveed, Harding, Lindsay P., Hemming, Karl, Laws, Andrew P. and Page, Michael I. (2005) Acylation versus sulfonylation in the inhibition of elastase by 3-oxo-beta-sultams. Journal of the American Chemical Society, 127 (25). pp. 8946-8947. ISSN 1520-5126


Ward, Roberta J. and Hemming, Karl (2014) Ethane-beta-Sultam Modifies the Activation of the Innate Immune System Induced by Intermittent Ethanol Administration in Female Adolescent Rats. Alcoholoism and Drug Dependence, 2 (2). p. 150. ISSN 2329-6488

Ward, Roberta J., Lallemand, Frederic, de Witte, Philippe, Chrichton, Robert R, Piette, Jacques, Tipton, Keith, Hemming, Karl, Pitard, Arnaud, Page, Michael I., Corte, Laura Della, Taylor, Deanna and Dexter, David (2011) Anti-inflammatory actions of a taurine analogue - ethane beta-sultam. Biochemical Pharmacology, 81 (6). pp. 743-751. ISSN 0006-2952

Waters, Laura J., Naz, S. and Hemming, Karl (2008) Calorimetric investigations of the hydrolytic degradation for a series of β-sultams. Journal of Thermal Analysis and Calorimetry, 93 (2). pp. 339-342. ISSN 14182874

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