A facile and highly stereoselective approach to a polycyclic isoindolinone ring system via an N-acyliminium ion cyclization reaction

Allin, Steven M.; Northfield, Christopher J.; Page, Michael I.; Slawin, Alexandra M.Z.

A facile and highly stereoselective approach to a polycyclic isoindolinone ring system via an N-acyliminium ion cyclization reaction

Allin, Steven M., Northfield, Christopher J., Page, Michael I. and Slawin, Alexandra M.Z. (1998) A facile and highly stereoselective approach to a polycyclic isoindolinone ring system via an N-acyliminium ion cyclization reaction. Tetrahedron Letters, 39 (27). pp. 4905-4908. ISSN 0040-4039

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Abstract

A highly diastereoselective synthesis of chiral ring-fused isoindolinone products, the skeleton of which is common to many naturally occurring and biologically active compounds, is achieved in only two synthetic steps from readily available precursors via an N-acyliminium ion cyclization reaction of an isoindolinone substrate.

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URI:

https://eprints.hud.ac.uk/id/eprint/6087

Title:

A facile and highly stereoselective approach to a polycyclic isoindolinone ring system via an N-acyliminium ion cyclization reaction

Creators:

Allin, Steven M., Northfield, Christopher J., Page, Michael I. and Slawin, Alexandra M.Z.

Identification Number:

10.1016/S0040-4039(98)00892-2

Official URL:

http://dx.doi.org/10.1016/S0040-4039(98)00892-2

Date: