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Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences

Parkinson, John A., Scott, Fraser J., Suckling, Colin J. and Wilson, Gail (2013) Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences. MedChemComm, 4 (7). p. 1105. ISSN 2040-2503

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Abstract

An antibacterial DNA minor groove binder is shown by NOE experiments to self-associate in aqueous solution at temperatures up to 80 °C in an anti-parallel, head-to-tail orientation as found in binding to duplex DNA oligomers

Item Type: Article
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences
Depositing User: Fraser Scott
Date Deposited: 15 Aug 2017 12:46
Last Modified: 15 Aug 2017 12:46
URI: http://eprints.hud.ac.uk/id/eprint/32654

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