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Synthesis of cleviolide and the scobinolides

Hollingworth, Gregory and Sweeney, Joseph B. (1993) Synthesis of cleviolide and the scobinolides. Synlett (7). pp. 463-465. ISSN 0936-5214

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The polyunsaturated 2(5H)-furanone natural products cleviolide (1) and (E)- and (Z)-scobinolide (2) and (3) have been efficiently synthesized in convergent fashion via palladiumcatalyzed coupling of 4-tributylstannyl-2(5H)-furanone (4) and 1-iodo-4-methylpent-3-en-1-yne (5).

Item Type: Article
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences
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Depositing User: Joseph Sweeney
Date Deposited: 09 Oct 2012 09:51
Last Modified: 28 Aug 2021 11:22


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