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Number of items: 52.

2017

Harmer, Jane, Qi, Xin, Toniolo, Gabriella, Patel, Aysha, Shaw, Hannah, Benson, Fiona E., Ginger, Michael L. and McKean, Paul G. (2017) Variation in Basal Body Localisation and Targeting of Trypanosome RP2 and FOR20 Proteins. Protist, 168 (4). pp. 452-466. ISSN 1434-4610

2016

Gabaldón, Toni, Ginger, Michael L. and Michels, Paul A.M. (2016) Peroxisomes in parasitic protists. Molecular and Biochemical Parasitology, 209 (1-2). pp. 35-45. ISSN 0166-6851

Jackson, Andrew P., Otto, Thomas D., Aslett, Martin, Armstrong, Stuart D., Bringaud, Frederic, Schlacht, Alexander, Hartley, Catherine, Sanders, Mandy, Wastling, Jonathan M., Dacks, Joel B., Acosta-Serrano, Alvaro, Field, Mark C., Ginger, Michael L. and Berriman, Matthew (2016) Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism. Current Biology, 26 (2). pp. 161-172. ISSN 0960-9822

2015

Sunter, J. D., Benz, C., Andre, J., Whipple, S., McKean, P. G., Gull, K., Ginger, Michael L. and Lukes, J. (2015) Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions. Journal of Cell Science, 128 (16). pp. 3117-3130. ISSN 0021-9533

Shameer, S. et al. (2015) TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Research, 43 (D1). D637-D644. ISSN 0305-1048

2014

Moran, J., McKean, P. G. and Ginger, Michael L. (2014) Eukaryotic Flagella: Variations in Form, Function, and Composition during Evolution. BioScience, 64 (12). pp. 1103-1114. ISSN 0006-3568

Ginger, Michael L. (2014) Protein moonlighting in parasitic protists. Biochemical Society Transactions, 42 (6). pp. 1734-1739. ISSN 0300-5127

Hayes, Polly, Varga, Vladimir, Olego-Fernandez, Sofia, Sunter, Jack, Ginger, Michael L. and Gull, Keith (2014) Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology. The Journal of Cell Biology, 206 (3). pp. 377-384. ISSN 0021-9525

Voncken, Frank, Brown, Robert W. B., Collingridge, Peter W., Gull, Keith, Rigden, Daniel J. and Ginger, Michael L. (2014) Evidence for Loss of a Partial Flagellar Glycolytic Pathway during Trypanosomatid Evolution. PLoS ONE, 9 (7). e103026. ISSN 1932-6203

Andre, J., Kerry, L., Qi, X., Hawkins, E., Drizyte, K., Ginger, Michael L. and McKean, P. G. (2014) An Alternative Model for the Role of RP2 Protein in Flagellum Assembly in the African Trypanosome. Journal of Biological Chemistry, 289 (1). pp. 464-475. ISSN 0021-9258

2013

Andre, J., Harrison, S., Towers, K., Qi, X., Vaughan, S., McKean, P. G. and Ginger, Michael L. (2013) The tubulin cofactor C family member TBCCD1 orchestrates cytoskeletal filament formation. Journal of Cell Science, 126 (23). pp. 5350-5356. ISSN 0021-9533

Koumandou, V. Lila, Wickstead, Bill, Ginger, Michael L., van der Giezen, Mark, Dacks, Joel B. and Field, Mark C. (2013) Molecular paleontology and complexity in the last eukaryotic common ancestor. Critical Reviews in Biochemistry and Molecular Biology, 48 (4). pp. 373-396. ISSN 1040-9238

Ginger, Michael L., Collingridge, Peter W., Brown, Robert W.B., Sproat, Rhona, Shaw, Michael K. and Gull, Keith (2013) Calmodulin is Required for Paraflagellar Rod Assembly and Flagellum-Cell Body Attachment in Trypanosomes. Protist, 164 (4). pp. 528-540. ISSN 1434-4610

Basu, S., Leonard, J. C., Desai, N., Mavridou, D. A. I., Tang, K. H., Goddard, A. D., Ginger, Michael L., Lukes, J. and Allen, J. W. A. (2013) Divergence of Erv1-Associated Mitochondrial Import and Export Pathways in Trypanosomes and Anaerobic Protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Clarke, Michael et al. (2013) Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biology, 14 (2). R11. ISSN 1465-6906

2012

Ginger, Michael L., Sam, Katharine A. and Allen, James W. A. (2012) Probing why trypanosomes assemble atypical cytochromecwith an AxxCH haem-binding motif instead of CxxCH. Biochemical Journal, 448 (2). pp. 253-260. ISSN 0264-6021

Jackson, A. P., Berry, A., Aslett, M., Allison, H. C., Burton, P., Vavrova-Anderson, J., Brown, R., Browne, H., Corton, N., Hauser, H., Gamble, J., Gilderthorp, R., Marcello, L., McQuillan, J., Otto, T. D., Quail, M. A., Sanders, M. J., van Tonder, A., Ginger, Michael L., Field, M. C., Barry, J. D., Hertz-Fowler, C. and Berriman, M. (2012) Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species. Proceedings of the National Academy of Sciences, 109 (9). pp. 3416-3421. ISSN 0027-8424

2011

Fritz-Laylin, Lillian K., Ginger, Michael L., Walsh, Charles, Dawson, Scott C. and Fulton, Chandler (2011) The Naegleria genome: a free-living microbial eukaryote lends unique insights into core eukaryotic cell biology. Research in Microbiology, 162 (6). pp. 607-618. ISSN 0923-2508

Brennand, Ana, Gualdrón-López, Melisa, Coppens, Isabelle, Rigden, Daniel J., Ginger, Michael L. and Michels, Paul A.M. (2011) Autophagy in parasitic protists: Unique features and drug targets. Molecular and Biochemical Parasitology, 177 (2). pp. 83-99. ISSN 0166-6851

Duszenko, Michael, Ginger, Michael L., Brennand, Ana, Gualdrón-López, Melisa, Colombo, María Isabel, Coombs, Graham H., Coppens, Isabelle, Jayabalasingham, Bamini, Langsley, Gordon, Lisboa de Castro, Solange, Menna-Barreto, Rubem, Mottram, Jeremy C., Navarro, Miguel, Rigden, Daniel J., Romano, Patricia S., Stoka, Veronika, Turk, Boris and Michels, Paul A.M. (2011) Autophagy in protists. Autophagy, 7 (2). pp. 127-158. ISSN 1554-8627

2010

Ginger, Michael L., Fritz-Laylin, Lillian K., Fulton, Chandler, Cande, W. Zacheus and Dawson, Scott C. (2010) Intermediary Metabolism in Protists: a Sequence-based View of Facultative Anaerobic Metabolism in Evolutionarily Diverse Eukaryotes. Protist, 161 (5). pp. 642-671. ISSN 1434-4610

Gluenz, Eva, Ginger, Michael L. and McKean, Paul G (2010) Flagellum assembly and function during the Leishmania life cycle. Current Opinion in Microbiology, 13 (4). pp. 473-479. ISSN 1369-5274

Collingridge, Peter W., Brown, Robert W. B. and Ginger, Michael L. (2010) Moonlighting enzymes in parasitic protozoa. Parasitology, 137 (09). pp. 1467-1475. ISSN 0031-1820

Fritz-Laylin, Lillian K., Prochnik, Simon E., Ginger, Michael L., Dacks, Joel B., Carpenter, Meredith L., Field, Mark C., Kuo, Alan, Paredez, Alex, Chapman, Jarrod, Pham, Jonathan, Shu, Shengqiang, Neupane, Rochak, Cipriano, Michael, Mancuso, Joel, Tu, Hank, Salamov, Asaf, Lindquist, Erika, Shapiro, Harris, Lucas, Susan, Grigoriev, Igor V., Cande, W. Zacheus, Fulton, Chandler, Rokhsar, Daniel S. and Dawson, Scott C. (2010) The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility. Cell, 140 (5). pp. 631-642. ISSN 0092-8674

Ginger, Michael L., McFadden, G. I. and Michels, P. A. M. (2010) Rewiring and regulation of cross-compartmentalized metabolism in protists. Philosophical Transactions of the Royal Society B: Biological Sciences, 365 (1541). pp. 831-845. ISSN 0962-8436

Ginger, Michael L., McFadden, G. I. and Michels, P. A. M. (2010) The evolution of organellar metabolism in unicellular eukaryotes. Philosophical Transactions of the Royal Society B: Biological Sciences, 365 (1541). pp. 693-698. ISSN 0962-8436

2009

Olego-Fernandez, Sofia, Vaughan, Sue, Shaw, Michael K., Gull, Keith and Ginger, Michael L. (2009) Cell Morphogenesis of Trypanosoma brucei Requires the Paralogous, Differentially Expressed Calpain-related Proteins CAP5.5 and CAP5.5V. Protist, 160 (4). pp. 576-590. ISSN 1434-4610

Rigden, Daniel J., Michels, Paul and Ginger, Michael L. (2009) Autophagy in protists: examples of secondary loss, lineage-specific innovations, and the conundrum of remodeling a single mitochondrion. Autophagy, 5 (6). pp. 784-794. ISSN 1554-8627

Fülöp, Vilmos, Sam, Katharine A., Ferguson, Stuart J., Ginger, Michael L. and Allen, James W. A. (2009) Structure of a trypanosomatid mitochondrial cytochrome cwith heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase. FEBS Journal, 276 (10). pp. 2822-2832. ISSN 1742-464X

Allen, James W. A., Sawyer, Elizabeth B., Ginger, Michael L., Barker, Paul D. and Ferguson, Stuart J. (2009) Variantc-type cytochromes as probes of the substrate specificity of theE. colicytochromecmaturation (Ccm) apparatus. Biochemical Journal, 419 (1). pp. 177-186. ISSN 0264-6021

2008

Ginger, Michael L., Portman, Neil and McKean, Paul G. (2008) Swimming with protists: perception, motility and flagellum assembly. Nature Reviews Microbiology, 6 (11). pp. 838-850. ISSN 1740-1526

Allen, James W.A., Ferguson, Stuart J. and Ginger, Michael L. (2008) Distinctive biochemistry in the trypanosome mitochondrial intermembrane space suggests a model for stepwise evolution of the MIA pathway for import of cysteine-rich proteins. FEBS Letters, 582 (19). pp. 2817-2825. ISSN 0014-5793

Long, Shaojun, Jirků, Milan, Mach, Jan, Ginger, Michael L., Sutak, Robert, Richardson, Des, Tachezy, Jan and Lukeš, Julius (2008) Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologues in trypanosomes. Molecular Microbiology, 69 (1). pp. 94-109. ISSN 0950-382X

Allen, James W. A., Jackson, Andrew P., Rigden, Daniel J., Willis, Antony C., Ferguson, Stuart J. and Ginger, Michael L. (2008) Order within a mosaic distribution of mitochondrial c-type cytochrome biogenesis systems? FEBS Journal, 275 (10). pp. 2385-2402. ISSN 1742-464X

2007

Griffiths, S., Portman, N., Taylor, P. R., Gordon, S., Ginger, Michael L. and Gull, K. (2007) RNA Interference Mutant Induction In Vivo Demonstrates the Essential Nature of Trypanosome Flagellar Function during Mammalian Infection. Eukaryotic Cell, 6 (7). pp. 1248-1250. ISSN 1535-9778

2006

Davidge, Jacqueline A., Chambers, Emma, Dickinson, Harriet A., Towers, Katie, Ginger, Michael L. and McKean, Paul G (2006) Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation. Journal of Cell Science, 119 (19). pp. 3935-3943. ISSN 0021-9533

Broadhead, Richard, Dawe, Helen R., Farr, Helen, Griffiths, Samantha, Hart, Sarah R., Portman, Neil, Shaw, Michael K., Ginger, Michael L., Gaskell, Simon J., McKean, Paul G. and Gull, Keith (2006) Flagellar motility is required for the viability of the bloodstream trypanosome. Nature, 440 (7081). pp. 224-227. ISSN 0028-0836

Ginger, Michael L. (2006) Niche metabolism in parasitic protozoa. Philosophical Transactions of the Royal Society B: Biological Sciences, 361 (1465). pp. 101-118. ISSN 0962-8436

2005

Ginger, Michael L. (2005) Trypanosomatid Biology and Euglenozoan Evolution: New Insights and Shifting Paradigms Revealed through Genome Sequencing. Protist, 156 (4). pp. 377-392. ISSN 1434-4610

Ginger, Michael L., Ngazoa, E. S., Pereira, C. A., Pullen, T. J., Kabiri, M., Becker, K., Gull, K. and Steverding, D. (2005) Intracellular Positioning of Isoforms Explains an Unusually Large Adenylate Kinase Gene Family in the Parasite Trypanosoma brucei. Journal of Biological Chemistry, 280 (12). pp. 11781-11789. ISSN 0021-9258

2004

Allen, James W. A., Ginger, Michael L. and Ferguson, Stuart J. (2004) Maturation of the unusual single-cysteine (XXXCH) mitochondrialc-type cytochromes found in trypanosomatids must occur through a novel biogenesis pathway. Biochemical Journal, 383 (3). pp. 537-542. ISSN 0264-6021

Briggs, Laura J, Davidge, Jacqueline A, Wickstead, Bill, Ginger, Michael L. and Gull, Keith (2004) More than one way to build a flagellum: comparative genomics of parasitic protozoa. Current Biology, 14 (15). R611-R612. ISSN 0960-9822

Pullen, Timothy J., Ginger, Michael L., Gaskell, Simon J. and Gull, Keith (2004) Protein Targeting of an Unusual, Evolutionarily Conserved Adenylate Kinase to a Eukaryotic Flagellum. Molecular Biology of the Cell, 15 (7). pp. 3257-3265. ISSN 1059-1524

2003

Roberts, C.W., McLeod, R., Rice, D.W., Ginger, Michael L., Chance, M.L. and Goad, L.J. (2003) Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa. Molecular and Biochemical Parasitology, 126 (2). pp. 129-142. ISSN 0166-6851

Barry, J.D., Ginger, Michael L., Burton, P. and McCulloch, R. (2003) Why are parasite contingency genes often associated with telomeres? International Journal for Parasitology, 33 (1). pp. 29-45. ISSN 0020-7519

2002

Ginger, Michael L., Blundell, P. A., Lewis, A. M., Browitt, A., Gunzl, A. and Barry, J. D. (2002) Ex Vivo and In Vitro Identification of a Consensus Promoter for VSG Genes Expressed by Metacyclic-Stage Trypanosomes in the Tsetse Fly. Eukaryotic Cell, 1 (6). pp. 1000-1009. ISSN 1535-9778

Conway, Colin, McCulloch, Richard, Ginger, Michael L., Robinson, Nicholas P., Browitt, Alison and Barry, J. David (2002) Ku Is Important for Telomere Maintenance, but Not for Differential Expression of Telomeric VSG Genes, in African Trypanosomes. Journal of Biological Chemistry, 277 (24). pp. 21269-21277. ISSN 0021-9258

2001

Ginger, Michael L., Chance, M. L., Sadler, I. H. and Goad, L. J. (2001) The Biosynthetic Incorporation of the Intact Leucine Skeleton into Sterol by the Trypanosomatid Leishmania mexicana. Journal of Biological Chemistry, 276 (15). pp. 11674-11682. ISSN 0021-9258

Ginger, Michael L., Billett, David S.M., Mackenzie, Karen L., Kiriakoulakis, Konstandinos, Neto, Renato R., K. Boardman, Daniel, Santos, Vera L.C.S., Horsfall, Ian M. and A. Wolff, George (2001) Organic matter assimilation and selective feeding by holothurians in the deep sea: some observations and comments. Progress in Oceanography, 50 (1-4). pp. 407-421. ISSN 0079-6611

2000

Ginger, Michael L., Prescott, Mark C., Reynolds, David G., Chance, Michael L. and Goad, L. John (2000) Utilization of leucine and acetate as carbon sources for sterol and fatty acid biosynthesis by Old and New World Leishmania species, Endotrypanum monterogeii and Trypanosoma cruzi. European Journal of Biochemistry, 267 (9). pp. 2555-2566. ISSN 0014-2956

Ginger, Michael L., Santos, Vera L.C.S. and Wolff, George A. (2000) A preliminary investigation of the lipids of abyssal holothurians from the north-east Atlantic Ocean. Journal of the Marine Biological Association of the UK, 80 (1). pp. 139-146. ISSN 0025-3154

1999

Ginger, Michael L., Chance, Michael L. and Goad, L. John (1999) Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. Biochemical Journal, 342 (2). p. 397. ISSN 0264-6021

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