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Items where Author is Arozarena Arozarena, Imanol

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Arozarena, Imanol, Goicoechea, I., Erice, O., Ferguson, J., Margison, G.P. and Wellbrock, C. (2014) Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. Molecular Cancer Therapeutics, 13 (154). ISSN 1535-7163


Ferguson, J., Arozarena, Imanol, Ehrhardt, M. and Wellbrock, C. (2013) Combination of MEK and SRC inhibition suppresses melanoma cell growth and invasion. Oncogene, 32 ((1)). pp. 86-96. ISSN 0950-9232

Smith, M.P., Ferguson, J., Arozarena, Imanol, Hayward, R., Marais, R., Chapman, A., Hurlstone, A. and Wellbrock, C. (2013) Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma. Journal of the National Cancer Institute, 105 ((1)). pp. 33-46. ISSN 1460-2105


Arozarena, Imanol, Bischof, H., Gilby, D., Belloni, B., Dummer, R. and Wellbrock, C. (2011) In melanoma, beta-catenin is a suppressor of invasion. Oncogene, 30 (45). ISSN 0950-9232

Arozarena, Imanol, Calvo, F. and Crespo, P. (2011) Ras, an Actor on Many Stages: Posttranslational Modifications, Localization, and Site-Specified Events. Genes & Cancer, 2 (3). pp. 182-194. ISSN 1947-6019

Arozarena, Imanol, Sanchez-Laorden, B., Packer, L., Hidalgo-Carcedo, C., Hayward, R., Viros, A., Sahai, E. and Marais, R. (2011) Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell, 19 (1). pp. 45-57. ISSN 1535-6108


Casar, B., Arozarena, Imanol, Sanz-Moreno, V., Pinto, A., Agudo-Ibáñez, l., Marais, R., Lewis, R.E., Berciano, M.T. and Crespo, P. (2009) Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins. Molecular and Cellular Biology, 29 (5). pp. 1338-1353. ISSN 0270-7306,


Pardo, O.E., Wellbrock, C., Khanzada, U.K., Aubert, M., Arozarena, Imanol, Davidson, S., Bowen, F., Parker, P.J., Filonenko, V.V., Gout, I.T., Sebire, N., Marais, R., Downward, J. and Seckl, M.J. (2006) FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2. Embo Journal, 25 (13). pp. 3078-3088. ISSN 0261-4189

Matallanas, D., Sanz-Moreno, V., Arozarena, Imanol, Calvo, F., Agudo-Ibáñez, L., Santos, E., Berciano, M.T. and Crespo, P. (2006) Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation. Molecular and Cellular Biology, 26 (1). pp. 100-116. ISSN 0270-7306,


Arozarena, Imanol, Matallanas, D., Berciano, M.T., Sanz-Moreno, V., Calvo, F., Muñoz, M.T., Egea, G., Lafarga, M. and Crespo, P. (2004) Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors. Molecular and Cellular Biology, 24 (4). pp. 1516-1530. ISSN 0270-7306,


Matallanas, D., Arozarena, Imanol, Berciano, M.T., Aaronson, D.S., Pellicer, A., Lafarga, M. and Crespo, P. (2003) Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization. Journal of Biological Chemistry, 278 (7). pp. 4572-4581. ISSN 0021-9258


Arozarena, Imanol, Matallanas, D. and Crespo, P. (2001) Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP. Journal of Biological Chemistry, 276 (34). pp. 21878-21884. ISSN 0021-9258


Arozarena, Imanol, Aaronson, D.S., Matallanas, D., Sanz, V., Ajenjo, N., Tenbaum, S.P., Teramoto, H., Ighishi, T., Zabala, J.C., Gutkind, J.S. and Crespo, P. (2000) The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF. Journal of Biological Chemistry, 275 (34). pp. 26441-26448. ISSN 0021-9258

Sanz, V., Arozarena, Imanol and Crespo, P. (2000) Distinct carboxy-termini confer divergent characteristics to the mitogen-activated protein kinase p38alpha and its splice isoform Mxi2. FEBS Letters, 474 (2). pp. 169-174. ISSN 0014-5793

Delgado, M.D., Vaque, J.P., Arozarena, Imanol, Lopez-Ilasaca, M.A., Martinez, C., Crespo, P. and Leon, J. (2000) H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism. Oncogene, 19 (6). pp. 783-790. ISSN 0950-9232

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