Martin, Anthony F., Morris, Jeffrey J. and Page, Michael I. (1976) Intra-and inter-molecular general base catalysis in the aminolysis of benzylpenicillin. Chemical Communications (13). pp. 495-496. ISSN 1359-7345

The rate law for the aminolysis of benzylpenicillin is obtained and Brønsted -values indicate that the general-base-catalysed reaction occurs with a stepwise proton-transfer step; intramolecular general base catalysis occurs in the reaction of ethylenediamine with penicillin.