Structural and functional investigation of molybdoflavoenzymes in evolutionary diverse organisms

Kadi, Ibrahim (2019) Structural and functional investigation of molybdoflavoenzymes in evolutionary diverse organisms. Masters thesis, University of Huddersfield.

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Abstract

The molybdoflavoenzymes (MFEs), aldehyde oxidase (AOX) and xanthine oxidoreductase (XOR) catalyse the oxidation of many drugs, environmental pollutants and N-heterocyclic compounds. MFEs are enzymes that contain flavin adenine dinucleotide (FAD), iron sulphur domain [2Fe-2S] and molybdenum cofactor domain (Moco). This research study examined the structural evolution of MFEs in chordates and the effects of polymorphisms on vertebrate MFEs. Numerous databases such as NCBI were used multiple alongside alignment software such as CLC Sequence Viewer and UGENE.

Information

URI:

https://eprints.hud.ac.uk/id/eprint/35091

URI:

https://eprints.hud.ac.uk/id/eprint/35091

URI:

https://eprints.hud.ac.uk/id/eprint/35091

Title:

Structural and functional investigation of molybdoflavoenzymes in evolutionary diverse organisms

Creators:

Kadi, Ibrahim

Date:

June 2019

Subjects:

Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology

Schools:

School of Applied Sciences

Library

Item Type:

Thesis

Qualification Level:

Masters

Depositing User:

Andrew Strike

Date Deposited:

19 Nov 2019 15:37

Revision:

Last Modified:

28 Aug 2021 14:45

Documents

FINAL THESIS - KADI.pdf - Accepted Version
Restricted to Repository staff only until 5 August 2029.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

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