Lucas, Stephanie J, Lord, Rianne M, Wilson, Rachel L, Phillips, Roger M, Sridharan, Visuvanathar and McGowan, Patrick C (2012) Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. Dalton Transactions, 41 (45). pp. 13800-13802. ISSN 1477-9226
Abstract

Several Ru-arene and Ir–Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

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