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Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands

Monteiro, DCF, Phillips, Roger, Crossley, BD, Fielden, J and Willans, CE (2012) Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands. Dalton Transactions, 41 (13). pp. 3720-3725. ISSN 1477-9226
Abstract

A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1. Bidentate ligands show enhanced cytotoxicity over monodentate and macrocyclic ligands.

Information
URI:
https://eprints.hud.ac.uk/id/eprint/23474
URI:
https://eprints.hud.ac.uk/id/eprint/23474
URI:
https://eprints.hud.ac.uk/id/eprint/23474
URI:
https://eprints.hud.ac.uk/id/eprint/23474
URI:
https://eprints.hud.ac.uk/id/eprint/23474
Title:
Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands
Creators:
Monteiro, DCF, Phillips, Roger, Crossley, BD, Fielden, J and Willans, CE
Identification Number:
DOI: 10.1039/c2dt12399a
Official URL:
http://dx.doi.org/10.1039/c2dt12399a
Date:
April 2012
Subjects:
R Medicine > RM Therapeutics. Pharmacology
Schools:
School of Applied Sciences
Library
Item Type:
Article
Depositing User:
Roger Phillips
Date Deposited:
26 Feb 2015 16:31
Revision:
16
Last Modified:
28 Aug 2021 18:27
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