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The Chemical Reactivity of β-Lactams, β-Sultams and β-Phospholactams

Page, Michael I. and Laws, Andrew P. (2000) The Chemical Reactivity of β-Lactams, β-Sultams and β-Phospholactams. Tetrahedron, 56 (31). pp. 5631-5637. ISSN 0040-4020
Abstract

β-Lactam antibiotics display a range of biological activities. The origin of this diverse biological activity is discussed with reference to the chemical reactivity of the small ring system. The reactions of β-sultams and β-phospholactams with simple nucleophiles are reported and their potential as mechanism based inhibitors of bacterial and mammalian serine proteases is described.

Information
URI:
https://eprints.hud.ac.uk/id/eprint/2259
URI:
https://eprints.hud.ac.uk/id/eprint/2259
Title:
The Chemical Reactivity of β-Lactams, β-Sultams and β-Phospholactams
Creators:
Page, Michael I. and Laws, Andrew P.
Identification Number:
10.1016/S0040-4020(00)00412-9
Official URL:
http://dx.doi.org/10.1016/S0040-4020(00)00412-9
Date:
2000
Subjects:
Q Science > Q Science (General)
Q Science > QD Chemistry
Schools:
School of Applied Sciences
School of Applied Sciences > Biomolecular Sciences Research Centre
Library
Item Type:
Article
Depositing User:
Sara Taylor
Date Deposited:
16 Oct 2008 15:44
Revision:
13
Last Modified:
28 Aug 2021 10:42
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