CuI-catalyzed cycloisomerization of propargyl amides

Alhalib, Ali and Moran, Wesley J. (2014) CuI-catalyzed cycloisomerization of propargyl amides. Organic & Biomolecular Chemistry, 12 (5). pp. 795-800. ISSN 1477-0520

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Abstract

The synthesis of substituted dihydrooxazoles by the CuI-catalyzed cycloisomerization of terminal propargyl amides is reported. The reaction has been shown to have good substrate scope and experiments to delineate the mechanism have been performed. Substrates containing a benzylic methylene were oxidized to the ketone under the reaction conditions.

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URI:

https://eprints.hud.ac.uk/id/eprint/19453

URI:

https://eprints.hud.ac.uk/id/eprint/19453

Title:

CuI-catalyzed cycloisomerization of propargyl amides

Creators:

Alhalib, Ali and Moran, Wesley J.

Identification Number:

10.1039/c3ob42030b

Official URL: