Preparation and ring-opening reactions ofN-diphenylphosphinyl vinyl aziridines

Jarvis, Ashley N., McLaren, Andrew B., Osborn, Helen M. I. and Sweeney, Joseph B. (2013) Preparation and ring-opening reactions ofN-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397

[+][-]

Abstract

Predominantly (E)-N-diphenylphosphinyl vinyl aziridines are prepared by a reaction of N-diphenylphosphinyl imines with α-bromoallyllithium in the presence of freshly fused ZnCl2. These aziridines undergo a ring-opening reaction with a variety of carbon and heteronucleophiles, in good yield, and generally with good regioselectivity.

Information

URI:

https://eprints.hud.ac.uk/id/eprint/18407

Title:

Preparation and ring-opening reactions ofN-diphenylphosphinyl vinyl aziridines

Creators:

Jarvis, Ashley N., McLaren, Andrew B., Osborn, Helen M. I. and Sweeney, Joseph B.

Identification Number:

10.3762/bjoc.9.98

Official URL:

http://dx.doi.org/10.3762/bjoc.9.98

Date: