Rahman, Rubina, Oxley, L. and Stephenson, John (2013) Persistent outer retinal fluid following non-posturing surgery for idiopathic macular hole. British Journal of Ophthalmology, 97 (11). pp. 1451-1454. ISSN 0007-1161

Purpose: To present the anatomical and visual outcomes of patients with hypo reflective cystic defects in outer fovea (OFD) in macular holes repaired with non-posturing vitrectomy and short term gas tamponade. To identify the incidence and risk factors for developing OFD foveal defect

Method: A prospective consecutive case series of 58 patients, undergoing macular hole surgery was undertaken. Any OFD on their two week post-operative OCT was measured, and in these patients OCT was performed monthly until resolution of OFD was observed.

Results: 27 eyes (46.6%) had an outer defect at 2 weeks, the presence of which was significantly associated with macular holes with larger base diameters preoperatively (p=0.006). All defects closed spontaneously without further intervention, and the final vision was not affected by the presence of an OFD. Visual recovery was only slightly (and not significantly) delayed by the presence of an outer defect.

Conclusions: This is the first study of outcomes of OFDs following macular hole surgery in patients who did not posture postoperatively. OFDs are common but do not adversely affect visual outcomes.

re-revised_May2013_final.pdf - Accepted Version

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