Richecoeur, Alexandre M.E. and Sweeney, Joseph B. (1998) Stannylfuranones in synthesis: Highly enantioselective preparation of (+)-hamabiwalactone B. Tetrahedron Letters, 39 (48). pp. 8901-8904. ISSN 0040-4039

An unambiguous and highly enantioselective total synthesis of the naturally-occurring 2(5H)-furanone hamabiwalactone B has been achieved. The key step is a Stille coupling of novel stannylfuranone2 with (E)-iodoalkene3. The enantiomeric purity of the synthetic natural product was ≥99%, as judged by chiral HPLC.

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