Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction

Maguire, Naomi, McLaren, Andrew and Sweeney, Joseph B. (2003) Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction. Synlett, 12. pp. 1898-1900. ISSN 0936-5214

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Abstract

(R)-3-Arylalanines may be prepared in high enantiomeric purity from N-dpp imines by a four-step reaction sequence involving asymmetric aza-Darzens reaction, dephosphinylation, hydrogenolysis and hydrolysis. The amino acids thus obtained were of >95% enantiomeric purity

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Title:

Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction

Creators:

Maguire, Naomi, McLaren, Andrew and Sweeney, Joseph B.

Identification Number:

10.1055/s-2003-41470

Official URL:

http://dx.doi.org/10.1055/s-2003-41470

Date:

29 September 2003

Subjects:

Q Science > QD Chemistry

Schools:

School of Applied Sciences

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Article

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Date Deposited:

18 Oct 2012 10:41

Revision:

8

Last Modified:

28 Aug 2021 11:22

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