Afshinjavid, S., Cluny, N., Okeke, I. and Javid, Farideh A. (2012) The effect of Enteroaggregative escherichia coli (eaec) on 5-Hydroxytryptamine (5-HT), carbachol and electrical field stimulation (EFS)-induced contraction in the rat ileum. pA2 Online, 10 (3). p. 350. ISSN 1741-1149

EAEC, are important diarrhoeal pathogens, being the most common cause of watery, persistent and
inflammatory diarrhoea (Okeke &Nataro, 2001). Several neurotransmitters such as 5-HT and
substance P have been implicated in the pathogenesis of diarrhoea induced by cholera toxin and clostridium difficile toxin A (Farthing 2000). The aim of the present study was to investigate the effect of EAEC on 5-HT, carbachol and EFS-induced contraction in the rat ileum.