Gabbutt, Christopher D., Hepworth, John D. and Heron, B. Mark (1992) Enamino ketones as precursors of functionalised 2H-thiopyrans and thiopyrano[2,3-c]- and [3,2-b]-benzothiopyrans. Journal of the Chemical Society, Perkin Transactions 1 (20). pp. 2603-2608. ISSN 0300-922X

Oxo enamino ketones obtained by treating active methylene compounds with N,N-dimethylformamide dimethyl acetal yield novel 2H-thiopyrans in a regioselective one pot thionation–[4 + 2]-cycloaddition sequence. Application of similar methodology to thiochroman-3-ones affords novel thiopyrano[2,3-c][1]benzothiopyrans and the [3,2-b] isomers.

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