Items where Author is Allison, Simon

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Allison, Simon J., Sadiq, Maria, Baronou, Efstathia, Cooper, Patricia A., Dunnill, Chris, Georgopoulos, Nikolaos T., Latif, Ayse, Shepherd, Samantha, Shnyder, Steve D., Stratford, Ian J., Wheelhouse, Richard, Willans, Charlotte and Phillips, Roger M. (2017) Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands. Cancer Letters. ISSN 0304-3835

Ayuso, Jose M., Virumbrales-Muñoz, María, Lacueva, Alodia, Lanuza, Pilar M., Checa-Chavarria, Elisa, Botella, Pablo, Fernández, Eduardo, Doblare, Manuel, Allison, Simon J., Phillips, Roger M., Pardo, Julián, Fernandez, Luis J. and Ochoa, Ignacio (2016) Development and characterization of a microfluidic model of the tumour microenvironment. Scientific Reports, 6. p. 36086. ISSN 2045-2322

Allison, Simon J., Knight, J.R.P., Granchi, C., Rani, R., Minutolo, F., Milner, J. and Phillips, R.M. (2014) Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53 independent pathways. Oncogenesis, 3 (e102). pp. 1-11. ISSN 2157-9024

Ahmadi, M., Ahmadihosseini, Z., Allison, Simon J., Begum, S., Rockley, K., Sadiq, M., Chintamaneni, S., Lokwani, R., Hughes, N. and Phillips, R. M. (2014) Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors. British Journal of Pharmacology, 171 (1). pp. 224-236. ISSN 0007-1188

Allison, Simon J. and Milner, Jo (2014) RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure. Molecular Therapy—Nucleic Acids, 2 (12). e141. ISSN 2162-2531

Allison, Simon J., Jiang, Ming and Milner, Jo (2009) Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells. Aging, 1 (3). pp. 316-327.

Allison, Simon J. and Milner, Jo (2007) SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways. Cell Cycle, 6 (21). pp. 2669-2677. ISSN 1538-4101

Allison, Simon J. and Milner, Jo (2004) Remodelling chromatin on a global scale: a novel protective function of p53. Carcinogenesis, 25 (9). pp. 1551-1557. ISSN 1460-2180

Allison, Simon J. and Milner, Jo (2003) Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. Cancer Research, 63 (20). pp. 6674-6679. ISSN 0008-5472

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Basri, Aida M., Lord, Rianne M., Allison, Simon J., Rodríguez-Bárzano, Andrea, Lucas, Stephanie J., Janeway, Felix D., Shepherd, Helena J., Pask, Christopher M., Phillips, Roger M. and McGowan, Patrick Columba (2017) Bis-Picolinamide ruthenium (III) dihalide complexes: dichloride to diiodide exchange generates single trans isomers with high potency and cancer cell selectivity. Chemistry - A European Journal. ISSN 0947-6539

Blagosklonny, Mikhail V., Lynch, Cian J., Shah, Zahid H., Allison, Simon J., Ahmed, Shafiq U., Ford, Jack, Warnock, Lorna J., Li, Han, Serrano, Manuel and Milner, Jo (2010) SIRT1 Undergoes Alternative Splicing in a Novel Auto-Regulatory Loop with p53. PLoS ONE, 5 (10). e13502. ISSN 1932-6203

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Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus and Falconer, Robert A. (2016) Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment. Scientific Reports, 6. p. 33026. ISSN 2045-2322

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Ford, Jack, Ahmed, Shafiq U., Allison, Simon J., Jiang, Ming and Milner, Jo (2008) JNK2-dependent regulation of SIRT1 protein stability. Cell Cycle, 7 (19). pp. 3091-3097. ISSN 1538-4101

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Johnston, I. M., Allison, Simon J., Morton, J. P., Schramm, L., Scott, P. H. and White, R. J. (2002) CK2 Forms a Stable Complex with TFIIIB and Activates RNA Polymerase III Transcription in Human Cells. Molecular and Cellular Biology, 22 (11). pp. 3757-3768. ISSN 0270-7306,

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Kaner, R.A., Allison, Simon J., Faulkner, A.D., Phillips, R.M., Roper, D.I., Shepherd, S.L., Simpson, D.H., Waterfield, N.R. and Scott, P. (2015) Anticancer metallohelices: nanomolar potency and high selectivity. Chemical Science. ISSN 2041-6520

Knight, J. R. P., Allison, Simon J. and Milner, Jo (2013) Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity. Open Biology, 3 (11). p. 130130. ISSN 2046-2441

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Lord, Rianne Michaela, Allison, Simon J., Rafferty, Karen, Ghandhi, Laura, Pask, Christopher M. and McGowan, Patrick C. (2016) Cytotoxic Hydrogen Bridged Ruthenium Quinaldamide Complexes Showing Induced Cancer Cell Death by Apoptosis. Dalton Trans.. ISSN 1477-9226

Lucas, Stephanie. J., Lord, Rianne M., Basri, Aida M., Allison, Simon J., Phillips, Roger M., Blacker, A. John and McGowan, Patrick C. (2016) Increasing anti-cancer activity with longer tether lengths of group 9 Cp* complexes. Dalton Transactions (16). ISSN 1477-9226

Lord, Rianne M, Hebden, Andrew J, Pask, Christopher M, Henderson, Imogen R, Allison, Simon J., Shepherd, Samantha L, Phillips, Roger M and McGowan, Patrick C (2015) Hypoxia Sensitive Metal β-Ketoiminate Complexes Showing Induced Single Strand DNA Breaks and Cancer Cell Death by Apoptosis. Journal of Medicinal Chemistry, 58 (12). pp. 4940-4953. ISSN 0022-2623

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Milner, Jo and Allison, Simon J. (2011) SIRT1, p53 and mitotic chromosomes. Cell Cycle, 10 (18). p. 3049. ISSN 1538-4101

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Shah, Z. H., Ahmed, S. U., Ford, J. R., Allison, Simon J., Knight, J. R. P. and Milner, Jo (2012) A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes. Molecular and Cellular Biology, 32 (3). pp. 704-716. ISSN 0270-7306

Sutcliffe, J. E., Brown, T. R., Allison, Simon J., Scott, P. H. and White, R. J. (2000) Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription. Molecular and Cellular Biology, 20 (24). pp. 9192-9202. ISSN 0270-7306

Sutcliffe, J. E., Cairns, Carol A., McLees, Angela, Allison, Simon J., Tosh, Kerrie and White, Robert J. (1999) RNA Polymerase III Transcription Factor IIIB Is a Target for Repression by Pocket Proteins p107 and p130. Molecular and Cellular Biology, 19 (6). pp. 4255-4261. ISSN 0270-7306

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Winter, A. G., Sourvinos, G., Allison, Simon J., Tosh, K., Scott, P. H., Spandidos, D. A. and White, R. J. (2000) RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumors. Proceedings of the National Academy of Sciences, 97 (23). pp. 12619-12624. ISSN 0027-8424