Items where Author is Mchugh, Patrick

2016

Buckley, David and McHugh, Patrick C (2016) Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine by DF Kisor, MD Kane, JN Talbot and JE Sprague. British Journal of Pharmacy, 1 (1). ISSN 2058-8356

Emamzadeh, Fatemeh Nouri, Aojula, Harmesh, McHugh, Patrick C and Allsopp, David (2016) Effects of different isoforms of apoE on aggregation of the α‐synuclein protein implicated in Parkinson’s disease. Neuroscience Letters, 618. pp. 146-151. ISSN 0304-3940

2015

McHugh, Patrick C and Buckley, David A. (2015) The Structure and Function of the Dopamine Transporter and its Role in CNS Diseases. In: Hormones and Transport Systems. Vitamins and the Immune System, 98 . Elsevier, pp. 339-369. ISBN 978-0-12-803008-0

2014

Zis, Panagiotis, McHugh, Patrick C, McQuillin, Andrew, Praticò, Domenico, Dickinson, Mark, Shende, Sima, Walker, Zuzana and Strydom, Andre (2014) Memory Decline in Down Syndrome and Its Relationship to iPF2alpha, a Urinary Marker of Oxidative Stress. PLoS ONE, 9 (6). e97709. ISSN 1932-6203

Airley, Rachel, McHugh, Patrick C, Evans, A.R., Harris, B., Winchester, L., Buffa, F.M., Al-Tameemi, W., Leek, R. and Harris, Adrian L. (2014) Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression. British Journal of Cancer, 110. pp. 715-723. ISSN 0007-0920

Joyce, Peter R., Stephenson, John, Kennedy, Martin, Mulder, Roger T. and McHugh, Patrick C (2014) The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder. Frontiers in Genetics: Behavioural and Psychiatric Genetics, 4 (313). ISSN 1664-8021

2013

Wright, Josephine A., McHugh, Patrick C, Pan, Siyi, Cunningham, Adam and Brown, David .R. (2013) Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. Molecular and Cellular Neuroscience, 57. pp. 33-41. ISSN 1044-7431

2012

McHugh, Patrick C, Wright, Josephine A., Williams, Robert J. and Brown, David R. (2012) Prion Protein Expression Alters APP Cleavage without Interaction with BACE-1. Neurochemistry International, 61 (5). pp. 672-680. ISSN 01970186

2011

McHugh, Patrick C (2011) The tetrahydrobiopterin pathway: a novel target for the treatment of depression. Pharmacogenomics, 12 (12). pp. 1625-1627. ISSN 1462-2416

Davies, Paul, McHugh, Patrick C, Hammond, Victoria J., Marken, Frank and Brown, David R. (2011) Contribution of Individual Histidines to Prion Protein Copper Binding. Biochemistry, 50 (50). pp. 10781-10791. ISSN 0006-2960

McHugh, Patrick C, Joyce, P R, Deng, X and Kennedy, M A (2011) A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. The Pharmacogenomics Journal, 11 (3). pp. 207-213. ISSN 1470-269X

McHugh, Patrick C, Wright, Josephine A. and Brown, David R. (2011) Transcriptional Regulation of the Beta-Synuclein 5′-Promoter Metal Response Element by Metal Transcription Factor-1. PLoS ONE, 6 (2). p. 17354. ISSN 1932-6203

2010

McHugh, Patrick C (2010) Tetrahydrobiopterin Pathway may Provide Novel Molecular Targets for Acute and Long Term Efficacy of Mood-Regulating Drugs. Current Pharmacogenomics and Personalized Medicine, 8 (3). pp. 174-181. ISSN 1875-6921

McHugh, Patrick C, Rogers, G., Glubb, D., Joyce, P. and Kennedy, M. (2010) Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine. Journal of Psychopharmacology, 24 (8). pp. 1243-1251. ISSN 0269-8811

Glubb, D M, McHugh, Patrick C, Deng, X, Joyce, P R and Kennedy, M A (2010) Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine. The Pharmacogenomics Journal, 10 (2). pp. 126-133. ISSN 1470-269X

2009

Wright, Josephine A., McHugh, Patrick C, Stockbridge, Mark, Lane, Samantha, Kralovicova, Silvia and Brown, David R. (2009) Activation and repression of prion protein expression by key regions of intron 1. Cellular and Molecular Life Sciences, 66 (23). pp. 3809-3820. ISSN 1420-682X

Joyce, Peter R., McHugh, Patrick C, Light, Katrina J., Rowe, Sarah, Miller, Allison L. and Kennedy, Martin A. (2009) Relationships Between Angry-Impulsive Personality Traits and Genetic Polymorphisms of the Dopamine Transporter. Biological Psychiatry, 66 (8). pp. 717-721. ISSN 0006-3223

McHugh, Patrick C, Joyce, Peter R. and Kennedy, Martin A. (2009) Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder. Pharmacogenetics and Genomics, 19 (5). pp. 330-337. ISSN 1744-6872

2008

McHugh, Patrick C, Rogers, Geraldine R., Glubb, Dylan M., Allington, Melanie D., Hughes, Mark, Joyce, Peter R. and Kennedy, Martin A. (2008) Downregulation ofCcnd1 and Hes6in rat hippocampus after chronic exposure to the antidepressant paroxetine. Acta Neuropsychiatrica, 20 (6). pp. 307-313. ISSN 0924-2708

McHugh, Patrick C, Rogers, Geraldine R., Loudon, Barbara, Glubb, Dylan M., Joyce, Peter R. and Kennedy, Martin A. (2008) Proteomic analysis of embryonic stem cell–derived neural cells exposed to the antidepressant paroxetine. Journal of Neuroscience Research, 86 (2). pp. 306-316. ISSN 0360-4012

2006

McHugh, Patrick C, Joyce, P.R. and Kennedy, Martin A. (2006) The proteomics of antidepressant drug response. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 141B (7). pp. 787-788. ISSN 1552-4841

Harris, T. P., Gomas, K. P., Weir, F., Holyoake, A. J., McHugh, Patrick C, Wu, M., Sin, Y., Sin, I. L. and Sin, F. Y. T. (2006) Molecular analysis of polymerase gamma gene and mitochondrial polymorphism in fertile and subfertile men. International Journal of Andrology, 29 (3). pp. 421-433. ISSN 0105-6263

Joyce, Peter R., McHugh, Patrick C, McKenzie, Janice M, Sullivan, Patrick F, Mulder, Roger T, Luty, Suzanne E, Carter, Janet D, Frampton, Christopher M A, Robert Cloninger, C., Miller, Allison M and Kennedy, Martin A. (2006) A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients. Psychological Medicine, 36 (06). p. 807. ISSN 0033-2917

2004

McHugh, Patrick C, Rogers, G.R., Joyce, P.R. and Kennedy, M.A. (2004) Embryonic stem cell-derived neurons : a model for antidepressant pharmacogenomics. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 130B (1). p. 158. ISSN 1552-4841

Bland, M.V., McHugh, Patrick C, Joyce, P.R. and Kennedy, M.A. (2004) Polymorphism analysis of serotonergic transcription factors. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 130B (1). p. 158. ISSN 1552-4841

2003

Armstrong, K.F., McHugh, Patrick C, Chinn, W., Frampton, E.R. and Walsh, P.J. (2003) Tussock moth species arriving on imported used vehicles determined by DNA analysis. New Zealand Plant Protection, 56. pp. 16-20. ISSN 1175-9003

2002

Holyoake, A. J., McHugh, Patrick C, Wu, M., O'Carroll, S., Benny, P., Sin, I. L. and Sin, F. Y. T. (2002) Research of single mitochondrial nucleotide substitutions in male infertility should consider human mitochondrial haplogroups - Reply. International Journal of Andrology, 25 (6). p. 374. ISSN 0105-6263

McHugh, Patrick C, Rogers, G.R., Cameron, V.A., Begg, E., Joyce, P.R. and Kennedy, M.A. (2002) Pharmacogenomics of antidepressant drug responses. American Journal of Medical Genetics. Part A, 114 (7). p. 881. ISSN 1552-4825

2001

Holyoake, A. J., McHugh, Patrick C, Wu, M., O'Carroll, S., Benny, P., Sin, I. L. and Sin, F. Y. T. (2001) High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men. International Journal of Andrology, 24 (3). pp. 175-182. ISSN 0105-6263

Sin, F. Y. T., Holyoake, A. J., McHugh, Patrick C, Wu, M., O'Carroll, S., Benny, P. and Sin, I. L. (2001) High Frequencies of Nucleotide Substitutions in mtDNA in Subfertile Men. In: Andrology in the 21st Century : Proceedings of the VIIth International. Medimond Medical, pp. 385-389. ISBN 9780970668011