Morjaria, Yamini, Irwin, William J., Barnett, Paul X, Chan, Rick S and Conway, Barbara R (2004) In vitro release of nicotine from chewing gum formulations. Dissolution Technologies, 11 (2). pp. 12-15. ISSN 1521-298X

Release of nicotine from conventional gums and from gums made using a directly compressible gum
base was studied using the European Pharmacopoeia apparatus for testing of medicated chewing gums.
It was found that gum base and the method of preparation used in a formulation were important factors when controlling the release of drugs from chewing gum.

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