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The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method.

Edgar, Benjamin, D'Angelo, Alessandra and Antonjievic, Milan D (2017) The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method. British Journal of Pharmacy, 2 (2). pp. 31-32. ISSN 2058-8356

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Abstract

Multiple three-component co-amorphous systems have been created via a melt- quench method. This has been confirmed by a single glass transition in the individual DSC traces and then reinforced by X-ray diffraction data, which show an absence of crystalline material.
ATR-FTIR has also been used to show a change in bonding vibrations between the physical mixtures and co-amorphous samples. The change in bonding vibrations indicates different molecular interactions within the co-amorphous materials.

Item Type: Article
Uncontrolled Keywords: co-amorphous, DSC, TGA, XRD, ATR-FTIR
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Schools: School of Applied Sciences
Depositing User: Megan Taylor
Date Deposited: 17 Jul 2018 11:12
Last Modified: 17 Jul 2018 11:45
URI: http://eprints.hud.ac.uk/id/eprint/34614

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