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The Synthesis and Chemistry of Azolobenzodiazepines

Hemming, Karl (2017) The Synthesis and Chemistry of Azolobenzodiazepines. In: Advances in Heterocyclic Chemistry. Advances in Heterocyclic Chemistry, 123 (123). Academic Press, pp. 63-103. ISBN 9780128120927

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Abstract

Approaches to the synthesis and applications of the azolobenzodiazepines have been reviewed with a particular focus on the imidazo-, pyrrolo-, pyrazolo-, and triazolo-fused systems. The review covers N-arylation, metal-catalyzed coupling
processes, radiolabeled synthesis, multicomponent reactions, and the synthesis of biologically active molecules. Key natural products covered are the fuligocandins,the circumdatins, and other pyrrolobenzodiazepines. The review also covers well-known pharmaceutical substances such as flumazenil, midazolam, SJG-136, and alprazolam.

Item Type: Book Chapter
Contributors:
ContributionNameEmailORCID
UNSPECIFIEDHemming, Karlk.hemming@hud.ac.ukUNSPECIFIED
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences > Biomolecular Sciences Research Centre
School of Applied Sciences
Related URLs:
Depositing User: Karl Hemming
Date Deposited: 20 Apr 2017 08:21
Last Modified: 20 Apr 2017 18:28
URI: http://eprints.hud.ac.uk/id/eprint/31707

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