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Powder Compaction: Compression Properties of Cellulose Ethers

Ghori, Muhammad Usman and Conway, Barbara R (2016) Powder Compaction: Compression Properties of Cellulose Ethers. British Journal of Pharmacy, 1 (1). ISSN 2058-8356

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Effective development of matrix tablets requires a comprehensive understanding of different raw material attributes and their impact on process parameters. Cellulose ethers (CE) are the most commonly used pharmaceutical excipients in the fabrication of hydrophilic matrices. The innate good compression and binding properties of CE enable matrices to be prepared using economical direct compression (DC) techniques. However, DC is sensitive to raw material attributes, thus, impacting the compaction process. This article critically reviews prior knowledge on the mechanism of powder compaction and the compression properties of cellulose ethers, giving timely insight into new developments in this field.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Schools: School of Applied Sciences
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Depositing User: Megan Taylor
Date Deposited: 15 Nov 2016 09:12
Last Modified: 01 Apr 2018 15:45


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