Powder Compaction: Compression Properties of Cellulose Ethers

Abstract

Effective development of matrix tablets requires a comprehensive understanding of different raw material attributes and their impact on process parameters. Cellulose ethers (CE) are the most commonly used pharmaceutical excipients in the fabrication of hydrophilic matrices. The innate good compression and binding properties of CE enable matrices to be prepared using economical direct compression (DC) techniques. However, DC is sensitive to raw material attributes, thus, impacting the compaction process. This article critically reviews prior knowledge on the mechanism of powder compaction and the compression properties of cellulose ethers, giving timely insight into new developments in this field.

How to Cite

Ghori, M. U. & Conway, B., (2016) “Powder Compaction: Compression Properties of Cellulose Ethers”, British Journal of Pharmacy 1(1). doi: https://doi.org/10.5920/bjpharm.2016.09

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Muhammad Usman Ghori (University of Huddersfield)
Barbara Conway (University of Huddersfield)

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This article has been peer reviewed.

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