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A prospective study of mental health outcomes in morbidly obese patients

Gillibrand, Warren P., Rajeswaran, C., Zaidi, S. Z., Muniyappa, S., Mohammad, M., Stephenson, John, Verma, S., Sloss, C., Covill, Carl and Holdich, Phil (2016) A prospective study of mental health outcomes in morbidly obese patients. Diabetic Medicine, 33 (S1). pp. 171-172. ISSN 0742-3071

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Aim: To determine if co-morbidities have an effect on mood in a cohort of morbidly obese patients.
Methods: Sequential linear regression analysis conducted on health and demographic data, using two validated anxiety/depression scales combined [Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7)] as the primary outcome.
Results: Complete outcome data was recorded on 410 patients. 211 (51.4%) had 1 or 2 reported co-morbidities; of which hypertension and anxiety/depression were the most common. One hundred and seven patients (26.4%) were recorded as having diabetes. The outcome measures of PHQ-9 and GAD-7 were found to be strongly and significantly correlated (r=0.822; p<0.001); hence analysis was conducted on a combined outcome. Occurrence of arthritis and anxiety/depression were both statistically significant at the 5% significance level (p=0.049 for arthritis; p<0.001 for anxiety/depression), with the presence of both conditions being associated with lower functionality. Age appeared to show some substantive association with the outcome (p=0.069); with increasing age being associated with slightly improved functionality. BMI, gender and the presence of other co-morbidities, including diabetes, did not exhibit any substantive relationship with the outcome measure.
Summary: There is insufficient evidence to conclude that either BMI, gender or diabetes affect scores measured on the combined PHQ-9/GAD-7 outcome. Of the various co-morbidities reported by patients, arthritis and, particularly, reported anxiety/depression have the greatest effect on combined scale scores.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Schools: School of Human and Health Sciences > Centre for Health and Social Care Research
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Depositing User: Warren Gillibrand
Date Deposited: 07 Mar 2016 15:15
Last Modified: 28 Aug 2021 17:19


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