Phylogeographic investigations: The role of trees in forensic genetics

Salas, Antonio, Bandelt, Hans-Jürgen, Macaulay, Vincent and Richards, Martin B. (2007) Phylogeographic investigations: The role of trees in forensic genetics. Forensic Science International, 168 (1). pp. 1-13. ISSN 03790738

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Abstract

The human mitochondrial DNA (mtDNA) genome is commonly analyzed in various disciplines, such as population, medical, and forensic genetics, but conceptual and scientific exchange between them is still limited. Here we review several aspects of the mtDNA phylogeny that are particularly – but not exclusively – of interest to the forensic community. Among the issues that arise, we emphasize the importance of integrating evolutionary concepts into the forensic routine. We also discuss topics such as mtDNA mutation-rate heterogeneity and the weight of evidence, ethnic affiliations of mtDNA profiles, and the abuse of reference databases. Finally, we show the usefulness of coding-region variation in a forensic context.

Item Type:	Article
Subjects:	G Geography. Anthropology. Recreation > GF Human ecology. Anthropogeography Q Science > Q Science (General) Q Science > QH Natural history > QH426 Genetics
Schools:	School of Applied Sciences
Related URLs:	Author
Depositing User:	Sara Taylor
Date Deposited:	14 Aug 2014 15:43
Last Modified:	14 Aug 2014 15:43
URI:	http://eprints.hud.ac.uk/id/eprint/21373

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