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CuI-catalyzed cycloisomerization of propargyl amides

Alhalib, Ali and Moran, Wesley J. (2014) CuI-catalyzed cycloisomerization of propargyl amides. Organic & Biomolecular Chemistry, 12 (5). pp. 795-800. ISSN 1477-0520

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The synthesis of substituted dihydrooxazoles by the CuI-catalyzed cycloisomerization of terminal propargyl amides is reported. The reaction has been shown to have good substrate scope and experiments to delineate the mechanism have been performed. Substrates containing a benzylic methylene were oxidized to the ketone under the reaction conditions.

Item Type: Article
Subjects: Q Science > QD Chemistry
Schools: School of Applied Sciences
Related URLs:
Depositing User: Wesley Moran
Date Deposited: 09 Jan 2014 14:34
Last Modified: 28 Aug 2021 11:35


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