Sweeney, Joseph B., Carter, Neil, Mabon, Ross, Walmsley, Rachel and Richecœur, Alexandre (2006) Double Coupling Reactions of 3,4-Bis(stannyl)furanone: Facile Preparation of Diaryl- and Dibenzylfuranones. Synlett, 2006 (11). pp. 1747-1749. ISSN 0936-5214
Metadata only available from this repository.Abstract
The palladium-catalyzed cross-coupling reaction of 3,4-bis(tributylstannyl)furan-2(5H)-one using chelating ligand or polar solvent gives mixtures of single and double coupled products, even when one equivalent of halide coupling partner is used. After optimization, the double coupling reaction was shown to be general, with the use of two equivalents of aryl iodides giving 3,4-disubstituted furanones, The reaction using benzyl bromides proceeds at lower temperatures than the corresponding coupling using aryl iodides, giving dibenzylfuranones. The methodology has been exemplified in a synthesis of (±)-hinokinin.
Item Type: | Article |
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Subjects: | Q Science > QD Chemistry |
Schools: | School of Applied Sciences |
Related URLs: | |
Depositing User: | Joseph Sweeney |
Date Deposited: | 18 Oct 2012 11:19 |
Last Modified: | 28 Aug 2021 11:22 |
URI: | http://eprints.hud.ac.uk/id/eprint/15223 |
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