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A facile route to pyrroles, isoindoles and hetero fused analogues

Gabbutt, Christopher D., Hepworth, John D., Heron, B. Mark and Pugh, Samantha L. (2002) A facile route to pyrroles, isoindoles and hetero fused analogues. Journal of the Chemical Society, Perkin Transactions 1 (24). pp. 2799-2808. ISSN 1472-7781

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Enamino acids derived from 1,2-dimethylaminomethylene- or 1,2-hydroxymethylene-carbonyl compounds and amino acids undergo a decarboxylative cyclisation to pyrroles, isoindoles and other fused pyrroles. A two atom ring expansion occurs preferentially with enamino acids from cyclohexane-1,3-diones and α-alkyl-α-amino acids leading to oxocino[2,3-c]pyrroles.

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Schools: School of Applied Sciences
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Depositing User: Sharon Beastall
Date Deposited: 25 Sep 2012 09:39
Last Modified: 28 Aug 2021 11:21


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