Direct aromatic tert-butylation during the synthesis of thiochroman-4-ones

Clayton, Stephen E., Gabbutt, Christopher D., Hepworth, John D. and Heron, B. Mark (1993) Direct aromatic tert-butylation during the synthesis of thiochroman-4-ones. Tetrahedron, 49 (4). pp. 939-946. ISSN 0040-4020

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Abstract

The synthesis of thiochroman-4-ones from thiophenols and 3-methylbut-2-enoic acid effected by methane sulphonic acid is accompanied by tert-butylation of the aromatic ring. 3-Arylthiobutanoic acids, available using β-butyrolactone, are efficiently cyclised in the same manner.

Item Type:	Article
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Schools:	School of Applied Sciences
Related URLs:	Author Author
Depositing User:	Sharon Beastall
Date Deposited:	20 Sep 2012 11:35
Last Modified:	18 Oct 2012 09:56
URI:	http://eprints.hud.ac.uk/id/eprint/14984

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