Synthetic approaches to 1,2,5-benzothiadiazepine 1,1-dioxides - sulfonamide analogues of the 1,4-benzodiazepines

Hemming, Karl and Loukou, Christina (2005) Synthetic approaches to 1,2,5-benzothiadiazepine 1,1-dioxides - sulfonamide analogues of the 1,4-benzodiazepines. Journal of chemical research (1). pp. 1-12. ISSN 1747-5198

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Abstract

Synthetic approaches to the 1,2,5-benzothiadiazepine 1,1-dioxides, sulfonamide analogues of the 1,4-benzodiazepines, are reviewed. The review incorporates the synthesis of bicyclic, tricyclic and tetracyclic systems, and includes approaches to sulfonamide analogues of the antitumour pyrrolobenzodiazepines, sulfonamide analogues of the tricyclic non-nucleosidic reverse transcriptase inhibiting benzodiazepines (such as nevirapine), and other systems of biological interest. Details of the reactions and biological activity of the 1,2,5-benzothiadiazepines are also given.

Item Type:	Article
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Schools:	School of Applied Sciences School of Applied Sciences > Biomolecular Sciences Research Centre
Related URLs:	Author
Depositing User:	Cherry Edmunds
Date Deposited:	24 Jul 2008 09:27
Last Modified:	07 Apr 2018 08:45
URI:	http://eprints.hud.ac.uk/id/eprint/1209

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