Nep, Elijah I and Conway, Barbara R (2012) Preformulation studies on grewia gum as a formulation excipient. Journal of Thermal Analysis and Calorimetry, 108 (1). pp. 197-205. ISSN 1388-6150
Metadata only available from this repository.Abstract
Grewia gum is a naturally occurring polysaccharide which has potential as a pharmaceutical excipient. Differential scanning calorimetry and Fourier transform infrared (FT-IR) spectroscopy techniques were used to examine the thermal and molecular behaviours, respectively, of mixtures of grewia gum with cimetidine, ibuprofen or standard excipients, to assess potential interactions. No disappearance or broadening of the melting endotherm was seen with cimetidine or ibuprofen. Similarly, there was no interaction between grewia gum and the standard excipients tested. The results obtained using thermal analyses were supported by FT-IR analysis of the material mixtures. Grewia gum is an inert natural polymer which can be used alone or in combination with other excipients in the formulation of pharmaceutical dosage forms
Item Type: | Article |
---|---|
Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
Schools: | School of Applied Sciences School of Human and Health Sciences > Institute for Skin Integrity and Infection Prevention |
Related URLs: | |
Depositing User: | Sara Taylor |
Date Deposited: | 20 Sep 2011 11:23 |
Last Modified: | 28 Aug 2021 11:10 |
URI: | http://eprints.hud.ac.uk/id/eprint/11515 |
Downloads
Downloads per month over past year
Repository Staff Only: item control page
![]() |
View Item |