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Studies on the anti-inflammatory properties of Entada abyssinica.

Olajide, Olumayokun A and Alada, A R (2001) Studies on the anti-inflammatory properties of Entada abyssinica. Fitoterapia, 72 (5). pp. 492-496. ISSN 0367-326X

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Abstract

The defatted methanolic extract of Entada abyssinica was evaluated for anti-inflammatory activity in acute and chronic models of inflammation. The extract (50-200 mg/kg, p.o.) exhibited dose-dependent and significant inhibition of both the carrageenan-induced rat paw oedema and granuloma tissue formation in rats. The extract (50-200 mg/kg, p.o.) was also found to inhibit the acetic acid-induced vascular permeability in a dose-dependent fashion in mice. This study demonstrated the anti-inflammatory activity of Entada abyssinica.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Schools: School of Applied Sciences
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Depositing User: Olumayokun Olajide
Date Deposited: 10 Nov 2010 11:32
Last Modified: 10 Nov 2010 11:32
URI: http://eprints.hud.ac.uk/id/eprint/8985

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