Search:
Computing and Library Services - delivering an inspiring information environment

Evaluation of a nanoemulsion-based formulation for respiratory delivery of budesonide by nebulizers

Amani, Amir, York, Peter, Chrystyn, Henry and Clark, Brian J. (2010) Evaluation of a nanoemulsion-based formulation for respiratory delivery of budesonide by nebulizers. A A P S PharmSciTech , 11 (3). pp. 1147-1151. ISSN 1530-9932

Metadata only available from this repository.

Abstract

The aim of this work was to evaluate the in vitro performance of a nebulized nanoemulsion formulation which had been optimised previously. To do so, a transparent nanoemulsion preparation containing 1.5 mg/ml of budesonide was prepared and diluted to achieve concentrations of 250 and 500 μg/ml budesonide. The in vitro characteristics of the diluted nanoemulsions were then compared with the commercially available suspension of budesonide (Pulmicort Respules®) when nebulized using a jet and a vibrating mesh nebulizer. A smaller MMAD with improved aerosol output was observed in the nanoemulsion preparations compared with the corresponding suspension formulations indicating an improved in vitro performance for the nanoemulsion-based preparations

Item Type: Article
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Schools: School of Applied Sciences
Related URLs:
Depositing User: Sharon Beastall
Date Deposited: 17 Sep 2010 12:58
Last Modified: 15 Nov 2010 11:53
URI: http://eprints.hud.ac.uk/id/eprint/8612

Item control for Repository Staff only:

View Item

University of Huddersfield, Queensgate, Huddersfield, HD1 3DH Copyright and Disclaimer All rights reserved ©