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Entropy, Binding Energy, and Enzymic Catalysis

Page, Michael I. (1977) Entropy, Binding Energy, and Enzymic Catalysis. Angewandte Chemie International Edition, 16 (7). pp. 449-459. ISSN 1433-7851

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Abstract

Why are enzyme-catalyzed reactions so much faster than uncatalyzed reactions, and why are enzymes so specific? What is the effect of mere approximation of enzyme and substrate, and what is the influence of the strain energy? Attempts to answer these questions have led to comparisons between entropy changes in intermolecular and intramolecular reactions, and to determinations of the intrinsic energy of the bond arising by non-covalent interaction between enzyme and substrate

Item Type: Article
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Schools: School of Applied Sciences
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Depositing User: Sharon Beastall
Date Deposited: 12 Nov 2009 12:20
Last Modified: 12 Nov 2009 12:20
URI: http://eprints.hud.ac.uk/id/eprint/6224

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