Tools
Tools
Morris, Jeffrey J. and Page, Michael I. (1978) Intramolecular nucleophilic and general acid catalysis in the hydrolysis of an amide. Chemical Communications (14). p. 591. ISSN 1359-7345
Metadata only available from this repository.Official URL: http://dx.doi.org/10.1039/C39780000591
DOI: 10.1039/C39780000591
Abstract
The relative effectiveness of intramolecular nucleophilic and general acid catalysis are compared in the hydroxide-ion catalysed hydrolysis of N-(2-amino-ethyl)-2-endo-hydroxy-6-endo-norbornamide in its amino protonated form; the rate enhancement of ca. 109 is due mainly to nucleophilic catalysis by the neighbouring hydroxy group with only a relatively minor contribution from the protonated amino group acting as a general acid.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Schools: | School of Applied Sciences |
| Related URLs: | |
| Depositing User: | Sharon Beastall |
| Date Deposited: | 11 Nov 2009 12:48 |
| Last Modified: | 11 Nov 2009 12:48 |
| URI: | http://eprints.hud.ac.uk/id/eprint/6175 |
Item control for Repository Staff only:
| View Item |