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Opening of the thiazolidine ring of penicillin derivatives

Davis, Andrew M. and Page, Michael I. (1985) Opening of the thiazolidine ring of penicillin derivatives. Chemical Communications (23). pp. 1702-1704. ISSN 1359-7345
Abstract

Penicilloic acid derivatives undergo two types of reversible thiazolidine ring opening reactions; in aqueous alkaline solution methyl benzylpenicilloate ring opens to give an enamine intermediate by a base-catalysed elimination process involving C-6-H whereas benzylpenicilloic acid epimerises at C-5 by unimolecular ring opening to form an intermediate iminium ion

Information
URI:
https://eprints.hud.ac.uk/id/eprint/6172
URI:
https://eprints.hud.ac.uk/id/eprint/6172
URI:
https://eprints.hud.ac.uk/id/eprint/6172
Title:
Opening of the thiazolidine ring of penicillin derivatives
Creators:
Davis, Andrew M. and Page, Michael I.
Identification Number:
https://doi.org/10.1039/C39850001702
Official URL:
http://dx.doi.org/10.1039/C39850001702
Date:
December 1985
Subjects:
Q Science > Q Science (General)
Q Science > QD Chemistry
Schools:
School of Applied Sciences
Library
Item Type:
Article
Depositing User:
Sharon Beastall
Date Deposited:
11 Nov 2009 12:30
Revision:
11
Last Modified:
28 Aug 2021 10:52
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