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Laws, Andrew P., Stone, J.R. and Page, Michael I. (1994) Large rate enhancement for the hydrolysis of a four-membered ring phosphonamidate. Chemical Communications (10). pp. 1223-1224. ISSN 1359-7345
Metadata only available from this repository.Official URL: http://dx.doi.org/10.1039/C39940001223
DOI: 10.1039/C39940001223
Abstract
Unlike -lactams a four-membered cyclic 1,2-azaphosphetidine shows enhanced hydrolytic reactivity compared with an acyclic analogue; the cyclic phosphonamidate 3 undergoes hydroxide-ion catalysed hydrolysis in water with endocyclic P–N fission; a corresponding acyclic derivative hydrolyses with P–O fission in basic solution, the rate difference between the cyclic and acyclic structures for P–N fission is greater than 5 × 108
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Schools: | School of Applied Sciences |
| Related URLs: | |
| Depositing User: | Sharon Beastall |
| Date Deposited: | 05 Nov 2009 14:04 |
| Last Modified: | 05 Nov 2009 14:04 |
| URI: | http://eprints.hud.ac.uk/id/eprint/6101 |
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