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Barker, C.V., Page, Michael I., Korn, Stewart R. and Monteith, Michael (1999) Esterase catalysed enantioselective ring closure. Chemical Communications (8). pp. 721-722. ISSN 1359-7345
Metadata only available from this repository.Official URL: http://dx.doi.org/10.1039/a901204d
DOI: 10.1039/a901204d
Abstract
Porcine liver esterase catalyses the reaction of -amino esters in water to give a mixture of the corresponding -lactam and the hydrolysis product, deacylation of the acyl enzyme intermediate by ring closure occurs with a high enantioselectivity giving an ee of 90% for the formation of (S)-5-phenyl-2-pyrrolidone from racemic ethyl 4-phenyl-4-aminobutanoate
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Schools: | School of Applied Sciences |
| Related URLs: | |
| Depositing User: | Sharon Beastall |
| Date Deposited: | 05 Nov 2009 12:23 |
| Last Modified: | 05 Nov 2009 12:23 |
| URI: | http://eprints.hud.ac.uk/id/eprint/6095 |
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