Lafont, Anne-Gaelle, Fitzpatrick, Thomas, Rankin, J. Cliff, Dufour, Sylvie and Fouchereau-Peron, Martine (2006) Possible role of calcitonin gene-related peptide in osmoregulation via the endocrine control of the gill in a teleost, the eel, Anguilla anguilla. Peptides, 27 (4). pp. 812-819. ISSN 0196-9781Metadata only available from this repository.
Osmoregulation is a major challenge in aquatic animals involving a complex endocrine control. We investigated the potential role of calcitonin gene-related peptide (CGRP, a neuromediator in mammals) in the endocrine control of the gill in a teleost, the eel. Transfer from freshwater to seawater induced an hyperosmolality and a concomitant large increase in plasma CGRP levels. Specific CGRP binding sites were characterized in the gill and their number was up-regulated after seawater transfer. This study suggests that the endocrine control of gill function during osmoregulation may represent an ancient role of CGRP in vertebrates.
|Subjects:||Q Science > Q Science (General)|
Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
|Schools:||School of Applied Sciences|
|Depositing User:||Sara Taylor|
|Date Deposited:||14 Mar 2008 12:30|
|Last Modified:||31 Oct 2008 09:47|
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