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What is the interrelation of protein structure and physical behaviour and how is it influenced by environmental conditions?

Belton, Daniel J. and Miller, Aline F. (2005) What is the interrelation of protein structure and physical behaviour and how is it influenced by environmental conditions? In: 7th World Congress of Chemical Engineering, 10-14 July 2005, SECC, Glasgow. (Unpublished)

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      Abstract

      Proteins are essential for life and as such have been deemed useful as therapeutic agents. However, the complexities that make proteins important for biological processes can also make their behaviour complicated. Such behaviour can make production, processing and formulation of protein pharmaceuticals problematic. A therapeutic protein test system has been examined using infrared spectroscopy and differential scanning calorimetry to increase understanding of its behaviour. It has been show that the protein thermally denatures at 47 °C and that this is accompanied by changes to the structure.

      Item Type: Conference or Workshop Item (Paper)
      Additional Information: Expanded abstract appears in 7th World Congress of Chemical Engineering Book of Abstracts
      Subjects: T Technology > TP Chemical technology
      Q Science > QD Chemistry
      Schools: School of Applied Sciences
      Related URLs:
      Depositing User: Graham Stone
      Date Deposited: 08 Jul 2009 16:10
      Last Modified: 28 Jul 2010 19:40
      URI: http://eprints.hud.ac.uk/id/eprint/5020

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