Camp, Jason, Dunsford, Jay J., Dacosta, Oliver S. G., Blundell, Rebecca K., Adams, James, Britton, Joshua, Smith, Robert J., Bousfield, Thomas W. and Fay, Michael W. (2016) Recyclable glucose-derived palladium(0) nanoparticles as in situ-formed catalysts for cross-coupling reactions in aqueous media. RSC Advances, 6 (20). pp. 16115-16121. ISSN 2046-2069
- Accepted Version
Restricted to Repository staff only until January 2017.
In situ-generated, glucose-derived palladium(0) nanoparticles were shown to be convenient and effective catalysts for aqueous Mizoroki-Heck, Sonogashira and Suzuki-Miyaura cross-coupling reactions. The addition of only 4-10 mol glucose to the reaction mixture lead to a significant increase in yield of the desired products in comparison to processes that omitted the renewable sugar. Interestingly, the Mizoroki-Heck reaction was observed to proceed in good yield even as the reaction reached acidic pH levels. Extensive analysis of the size and morphology of the in situ-formed palladium nanoparticles using advanced analytical techniques showed that the zero valent metal was surrounded by hydrophilic hydroxyl groups. The increased aqueous phase affinity afforded by these groups allowed for facile recycling of the catalyst.
|Subjects:||Q Science > QD Chemistry|
|Schools:||School of Applied Sciences|
|Depositing User:||Jason Camp|
|Date Deposited:||14 Apr 2016 10:50|
|Last Modified:||01 Dec 2016 01:54|
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