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Nasal Drug Delivery Systems: An Overview

Ghori, Muhammad U., Mahdi, Mohammed H., Smith, Alan M. and Conway, Barbara R. (2015) Nasal Drug Delivery Systems: An Overview. American Journal of Pharmacological Sciences, 3 (5). pp. 110-119. ISSN 2327-6711

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Abstract

Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades. Intra-nasal administration of drugs offers an interesting alternative for achieving systemic therapeutic effects of drugs that are comparable to the parenteral route, which can be inconvenient at times or oral administration, which can result in unacceptably low drug bioavailability. So, it is important to understand the potential and limitations of various nasal drug delivery systems. Therefore, the aim of this review article is to discuss the various pharmaceutical dosage forms that have the potential to be utilised for local or systemic drug administration. It is intuitively expected that this review will help to understand and further to develop suitable intra-nasal formulations to achieve specific therapeutic objectives.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Schools: School of Applied Sciences
School of Human and Health Sciences > Institute for Skin Integrity and Infection Prevention
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Depositing User: Muhammad Ghori
Date Deposited: 07 Dec 2015 10:39
Last Modified: 31 Mar 2016 14:00
URI: http://eprints.hud.ac.uk/id/eprint/26635

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